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2mjn

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'''Unreleased structure'''
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{{STRUCTURE_2mjn| PDB=2mjn | SCENE= }}
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===Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1===
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{{ABSTRACT_PUBMED_24682828}}
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The entry 2mjn is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/TIA1_HUMAN TIA1_HUMAN]] Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
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Authors: Sattler, M., Wang, I.
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==About this Structure==
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[[2mjn]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJN OCA].
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Description: Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1
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==Reference==
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<ref group="xtra">PMID:024682828</ref><references group="xtra"/><references/>
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[[Category: Sattler, M.]]
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[[Category: Wang, I.]]
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[[Category: Rna binding protein]]
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[[Category: Rrm]]
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[[Category: Tia-1]]

Revision as of 06:32, 9 April 2014

Template:STRUCTURE 2mjn

Contents

Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1

Template:ABSTRACT PUBMED 24682828

Function

[TIA1_HUMAN] Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.

About this Structure

2mjn is a 1 chain structure. Full experimental information is available from OCA.

Reference

  • Wang I, Hennig J, Jagtap PK, Sonntag M, Valcarcel J, Sattler M. Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1. Nucleic Acids Res. 2014 Mar 25. PMID:24682828 doi:http://dx.doi.org/10.1093/nar/gku193

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OCA

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