1a3c
From Proteopedia
(Difference between revisions)
m (Protected "1a3c" [edit=sysop:move=sysop]) |
|||
Line 1: | Line 1: | ||
- | [[Image:1a3c.png|left|200px]] | ||
- | |||
- | <!-- | ||
- | The line below this paragraph, containing "STRUCTURE_1a3c", creates the "Structure Box" on the page. | ||
- | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
- | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
- | or leave the SCENE parameter empty for the default display. | ||
- | --> | ||
{{STRUCTURE_1a3c| PDB=1a3c | SCENE= }} | {{STRUCTURE_1a3c| PDB=1a3c | SCENE= }} | ||
- | |||
===PYRR, THE BACILLUS SUBTILIS PYRIMIDINE BIOSYNTHETIC OPERON REPRESSOR, DIMERIC FORM=== | ===PYRR, THE BACILLUS SUBTILIS PYRIMIDINE BIOSYNTHETIC OPERON REPRESSOR, DIMERIC FORM=== | ||
+ | {{ABSTRACT_PUBMED_9551555}} | ||
- | + | ==Function== | |
- | + | [[http://www.uniprot.org/uniprot/PYRR_BACSU PYRR_BACSU]] Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.[HAMAP-Rule:MF_01219] Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.[HAMAP-Rule:MF_01219] | |
- | + | ||
- | + | ||
- | - | + | |
- | + | ||
==About this Structure== | ==About this Structure== | ||
Line 22: | Line 10: | ||
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID:009551555</ref>< | + | <ref group="xtra">PMID:009551555</ref><references group="xtra"/><references/> |
[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
[[Category: Smith, J L.]] | [[Category: Smith, J L.]] |
Revision as of 06:32, 10 April 2014
Contents |
PYRR, THE BACILLUS SUBTILIS PYRIMIDINE BIOSYNTHETIC OPERON REPRESSOR, DIMERIC FORM
Template:ABSTRACT PUBMED 9551555
Function
[PYRR_BACSU] Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.[HAMAP-Rule:MF_01219] Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.[HAMAP-Rule:MF_01219]
About this Structure
1a3c is a 1 chain structure with sequence from Bacillus subtilis. Full crystallographic information is available from OCA.
Reference
- Tomchick DR, Turner RJ, Switzer RL, Smith JL. Adaptation of an enzyme to regulatory function: structure of Bacillus subtilis PyrR, a pyr RNA-binding attenuation protein and uracil phosphoribosyltransferase. Structure. 1998 Mar 15;6(3):337-50. PMID:9551555