1cm9

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[[Image:1cm9.png|left|200px]]
 
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{{STRUCTURE_1cm9| PDB=1cm9 | SCENE= }}
{{STRUCTURE_1cm9| PDB=1cm9 | SCENE= }}
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===CRYSTAL STRUCTURE OF VIRAL MACROPHAGE INFLAMMATORY PROTEIN-II===
===CRYSTAL STRUCTURE OF VIRAL MACROPHAGE INFLAMMATORY PROTEIN-II===
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{{ABSTRACT_PUBMED_11041848}}
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==Function==
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[[http://www.uniprot.org/uniprot/VMI2_HHV8 VMI2_HHV8]] Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions.
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{{ABSTRACT_PUBMED_11041848}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:011041848</ref><references group="xtra"/>
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<ref group="xtra">PMID:011041848</ref><references group="xtra"/><references/>
[[Category: Human herpesvirus 8]]
[[Category: Human herpesvirus 8]]
[[Category: Fernandez, E J.]]
[[Category: Fernandez, E J.]]

Revision as of 06:32, 10 April 2014

Template:STRUCTURE 1cm9

Contents

CRYSTAL STRUCTURE OF VIRAL MACROPHAGE INFLAMMATORY PROTEIN-II

Template:ABSTRACT PUBMED 11041848

Function

[VMI2_HHV8] Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions.

About this Structure

1cm9 is a 2 chain structure with sequence from Human herpesvirus 8. Full crystallographic information is available from OCA.

Reference

  • Fernandez EJ, Wilken J, Thompson DA, Peiper SC, Lolis E. Comparison of the structure of vMIP-II with eotaxin-1, RANTES, and MCP-3 suggests a unique mechanism for CCR3 activation. Biochemistry. 2000 Oct 24;39(42):12837-44. PMID:11041848

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OCA

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