1aca

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[[Image:1aca.png|left|200px]]
 
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{{STRUCTURE_1aca| PDB=1aca | SCENE= }}
{{STRUCTURE_1aca| PDB=1aca | SCENE= }}
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===THREE-DIMENSIONAL STRUCTURE OF THE COMPLEX BETWEEN ACYL-COENZYME A BINDING PROTEIN AND PALMITOYL-COENZYME A===
===THREE-DIMENSIONAL STRUCTURE OF THE COMPLEX BETWEEN ACYL-COENZYME A BINDING PROTEIN AND PALMITOYL-COENZYME A===
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{{ABSTRACT_PUBMED_8503960}}
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==Function==
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[[http://www.uniprot.org/uniprot/ACBP_BOVIN ACBP_BOVIN]] Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.<ref>PMID:11491287</ref>
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{{ABSTRACT_PUBMED_8503960}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:008503960</ref><references group="xtra"/>
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<ref group="xtra">PMID:008503960</ref><references group="xtra"/><references/>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Andersen, K V.]]
[[Category: Andersen, K V.]]

Revision as of 06:38, 10 April 2014

Template:STRUCTURE 1aca

Contents

THREE-DIMENSIONAL STRUCTURE OF THE COMPLEX BETWEEN ACYL-COENZYME A BINDING PROTEIN AND PALMITOYL-COENZYME A

Template:ABSTRACT PUBMED 8503960

Function

[ACBP_BOVIN] Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.[1]

About this Structure

1aca is a 1 chain structure with sequence from Bos taurus. Full experimental information is available from OCA.

Reference

  • Kragelund BB, Andersen KV, Madsen JC, Knudsen J, Poulsen FM. Three-dimensional structure of the complex between acyl-coenzyme A binding protein and palmitoyl-coenzyme A. J Mol Biol. 1993 Apr 20;230(4):1260-77. PMID:8503960 doi:http://dx.doi.org/10.1006/jmbi.1993.1240
  1. van Aalten DM, Milne KG, Zou JY, Kleywegt GJ, Bergfors T, Ferguson MA, Knudsen J, Jones TA. Binding site differences revealed by crystal structures of Plasmodium falciparum and bovine acyl-CoA binding protein. J Mol Biol. 2001 May 25;309(1):181-92. PMID:11491287 doi:10.1006/jmbi.2001.4749

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