3lg0
From Proteopedia
(Difference between revisions)
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===Structure of Plasmodium falciparum ornithine delta-aminotransferase=== | ===Structure of Plasmodium falciparum ornithine delta-aminotransferase=== | ||
{{ABSTRACT_PUBMED_20673832}} | {{ABSTRACT_PUBMED_20673832}} | ||
| + | |||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/OAT_PLAFD OAT_PLAFD]] The enzyme has a very narrow substrate specificity and can only catalyze the transamination of alpha-ketoglutarate with ornithine or N-acetylornithine and of glutamate-5-semialdehyde with glutamate and alanine (By similarity). | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3lg0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3lg0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Plafd Plafd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LG0 OCA]. |
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:020673832</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:020673832</ref><references group="xtra"/><references/> | ||
[[Category: Ornithine aminotransferase]] | [[Category: Ornithine aminotransferase]] | ||
| - | [[Category: | + | [[Category: Plafd]] |
[[Category: Becker, K.]] | [[Category: Becker, K.]] | ||
[[Category: Fritz-Wolf, K.]] | [[Category: Fritz-Wolf, K.]] | ||
Revision as of 07:50, 16 April 2014
Contents |
Structure of Plasmodium falciparum ornithine delta-aminotransferase
Template:ABSTRACT PUBMED 20673832
Function
[OAT_PLAFD] The enzyme has a very narrow substrate specificity and can only catalyze the transamination of alpha-ketoglutarate with ornithine or N-acetylornithine and of glutamate-5-semialdehyde with glutamate and alanine (By similarity).
About this Structure
3lg0 is a 4 chain structure with sequence from Plafd. Full crystallographic information is available from OCA.
Reference
- Jortzik E, Fritz-Wolf K, Sturm N, Hipp M, Rahlfs S, Becker K. Redox regulation of Plasmodium falciparum ornithine delta-aminotransferase. J Mol Biol. 2010 Sep 17;402(2):445-59. Epub 2010 Jul 29. PMID:20673832 doi:10.1016/j.jmb.2010.07.039
Categories: Ornithine aminotransferase | Plafd | Becker, K. | Fritz-Wolf, K. | Jortzik, E. | Stumpf, M. | Activation of plasmodium falciparum ornithine delta-aminotransferase | Alpha-ketoglutarate | Aminotransferase | Delta-aminotransferase | Ornithine | Plasmodium falciparum | Pyridoxal phosphate | Pyridoxal-5-phosphate-dependent enzyme | Transferase
