3n50

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Revision as of 08:04, 16 April 2014

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Template:STRUCTURE 3n50

Contents 1 Human Early B-cell factor 3 (EBF3) IPT/TIG and HLHLH domains 2 Function 3 About this Structure 4 Reference

Human Early B-cell factor 3 (EBF3) IPT/TIG and HLHLH domains

Template:ABSTRACT PUBMED 20592035

Function

[COE3_HUMAN] Transcriptional activator which recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3' (By similarity).

About this Structure

3n50 is a 6 chain structure with sequence from Human. Full crystallographic information is available from OCA.

Reference

• Siponen MI, Wisniewska M, Lehtio L, Johansson I, Svensson L, Raszewski G, Nilsson L, Sigvardsson M, Berglund H. Structural determination of functional domains in early B-cell factor (EBF) family of transcription factors reveals similarities to Rel DNA-binding proteins and a novel dimerization motif. J Biol Chem. 2010 Aug 20;285(34):25875-9. Epub 2010 Jun 30. PMID:20592035 doi:10.1074/jbc.C110.150482