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1xqo

From Proteopedia

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[[Image:1xqo.png|left|200px]]
 
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{{STRUCTURE_1xqo| PDB=1xqo | SCENE= }}
{{STRUCTURE_1xqo| PDB=1xqo | SCENE= }}
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===Crystal structure of native Pa-AGOG, 8-oxoguanine DNA glycosylase from Pyrobaculum aerophilum===
===Crystal structure of native Pa-AGOG, 8-oxoguanine DNA glycosylase from Pyrobaculum aerophilum===
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{{ABSTRACT_PUBMED_15642264}}
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{{ABSTRACT_PUBMED_15642264}}
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==Function==
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[[http://www.uniprot.org/uniprot/AGOG_PYRAE AGOG_PYRAE]] DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double-stranded DNA substrates.<ref>PMID:15604455</ref>
==About this Structure==
==About this Structure==
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[[1xqo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrobaculum_aerophilum Pyrobaculum aerophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XQO OCA].
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[[1xqo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_51768 Atcc 51768]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XQO OCA].
==See Also==
==See Also==
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==Reference==
==Reference==
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<ref group="xtra">PMID:015642264</ref><references group="xtra"/>
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<ref group="xtra">PMID:015642264</ref><references group="xtra"/><references/>
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[[Category: Pyrobaculum aerophilum]]
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[[Category: Atcc 51768]]
[[Category: Jiricny, J.]]
[[Category: Jiricny, J.]]
[[Category: Kostrewa, D.]]
[[Category: Kostrewa, D.]]

Revision as of 08:07, 16 April 2014

Template:STRUCTURE 1xqo

Contents

Crystal structure of native Pa-AGOG, 8-oxoguanine DNA glycosylase from Pyrobaculum aerophilum

Template:ABSTRACT PUBMED 15642264

Function

[AGOG_PYRAE] DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double-stranded DNA substrates.[1]

About this Structure

1xqo is a 1 chain structure with sequence from Atcc 51768. Full crystallographic information is available from OCA.

See Also

Reference

  • Lingaraju GM, Sartori AA, Kostrewa D, Prota AE, Jiricny J, Winkler FK. A DNA glycosylase from Pyrobaculum aerophilum with an 8-oxoguanine binding mode and a noncanonical helix-hairpin-helix structure. Structure. 2005 Jan;13(1):87-98. PMID:15642264 doi:10.1016/j.str.2004.10.011
  1. ↑ Sartori AA, Lingaraju GM, Hunziker P, Winkler FK, Jiricny J. Pa-AGOG, the founding member of a new family of archaeal 8-oxoguanine DNA-glycosylases. Nucleic Acids Res. 2004 Dec 16;32(22):6531-9. Print 2004. PMID:15604455 doi:http://dx.doi.org/10.1093/nar/gkh995

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