4oog
From Proteopedia
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m (Protected "4oog" [edit=sysop:move=sysop]) |
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- | + | {{STRUCTURE_4oog| PDB=4oog | SCENE= }} | |
+ | ===Crystal structure of yeast RNase III (Rnt1p) complexed with the product of dsRNA processing=== | ||
+ | {{ABSTRACT_PUBMED_24703949}} | ||
- | + | ==Function== | |
+ | [[http://www.uniprot.org/uniprot/RNT1_YEAST RNT1_YEAST]] DsRNA-specific nuclease that cleaves eukaryotic pre-ribosomal RNA at the U3 snoRNP-dependent A0 site in the 5'-external transcribed spacer (ETS) and in the 3'-ETS. In vitro, cleaves synthetic 5'-ETS RNA A0 site in the absence of snoRNA or other factors. Has an essential growth function in addition to pre-rRNA processing. | ||
- | + | ==About this Structure== | |
+ | [[4oog]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OOG OCA]. | ||
- | + | ==Reference== | |
+ | <ref group="xtra">PMID:024703949</ref><references group="xtra"/><references/> | ||
+ | [[Category: Ribonuclease III]] | ||
+ | [[Category: Ji, X.]] | ||
+ | [[Category: Liang, Y H.]] | ||
+ | [[Category: Double-stranded rna]] | ||
+ | [[Category: Double-stranded rna-binding domain]] | ||
+ | [[Category: Dsrna-specific rnase]] | ||
+ | [[Category: Endoribonuclease]] | ||
+ | [[Category: Hydrolase-rna complex]] | ||
+ | [[Category: Ribonuclease iii domain]] | ||
+ | [[Category: Rnase:rna complex]] |
Revision as of 09:42, 16 April 2014
Contents |
Crystal structure of yeast RNase III (Rnt1p) complexed with the product of dsRNA processing
Template:ABSTRACT PUBMED 24703949
Function
[RNT1_YEAST] DsRNA-specific nuclease that cleaves eukaryotic pre-ribosomal RNA at the U3 snoRNP-dependent A0 site in the 5'-external transcribed spacer (ETS) and in the 3'-ETS. In vitro, cleaves synthetic 5'-ETS RNA A0 site in the absence of snoRNA or other factors. Has an essential growth function in addition to pre-rRNA processing.
About this Structure
4oog is a 4 chain structure. Full crystallographic information is available from OCA.
Reference
- Liang YH, Lavoie M, Comeau MA, Abou Elela S, Ji X. Structure of a Eukaryotic RNase III Postcleavage Complex Reveals a Double-Ruler Mechanism for Substrate Selection. Mol Cell. 2014 Apr 2. pii: S1097-2765(14)00211-1. doi:, 10.1016/j.molcel.2014.03.006. PMID:24703949 doi:http://dx.doi.org/10.1016/j.molcel.2014.03.006