4oog

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m (Protected "4oog" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4oog| PDB=4oog | SCENE= }}
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===Crystal structure of yeast RNase III (Rnt1p) complexed with the product of dsRNA processing===
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{{ABSTRACT_PUBMED_24703949}}
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The entry 4oog is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/RNT1_YEAST RNT1_YEAST]] DsRNA-specific nuclease that cleaves eukaryotic pre-ribosomal RNA at the U3 snoRNP-dependent A0 site in the 5'-external transcribed spacer (ETS) and in the 3'-ETS. In vitro, cleaves synthetic 5'-ETS RNA A0 site in the absence of snoRNA or other factors. Has an essential growth function in addition to pre-rRNA processing.
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Authors: Liang, Y.-H., Ji, X.
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==About this Structure==
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[[4oog]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OOG OCA].
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Description: Crystal structure of yeast RNase III (Rnt1p) complexed with the product of dsRNA processing
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==Reference==
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<ref group="xtra">PMID:024703949</ref><references group="xtra"/><references/>
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[[Category: Ribonuclease III]]
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[[Category: Ji, X.]]
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[[Category: Liang, Y H.]]
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[[Category: Double-stranded rna]]
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[[Category: Double-stranded rna-binding domain]]
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[[Category: Dsrna-specific rnase]]
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[[Category: Endoribonuclease]]
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[[Category: Hydrolase-rna complex]]
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[[Category: Ribonuclease iii domain]]
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[[Category: Rnase:rna complex]]

Revision as of 09:42, 16 April 2014

Template:STRUCTURE 4oog

Contents

Crystal structure of yeast RNase III (Rnt1p) complexed with the product of dsRNA processing

Template:ABSTRACT PUBMED 24703949

Function

[RNT1_YEAST] DsRNA-specific nuclease that cleaves eukaryotic pre-ribosomal RNA at the U3 snoRNP-dependent A0 site in the 5'-external transcribed spacer (ETS) and in the 3'-ETS. In vitro, cleaves synthetic 5'-ETS RNA A0 site in the absence of snoRNA or other factors. Has an essential growth function in addition to pre-rRNA processing.

About this Structure

4oog is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  • Liang YH, Lavoie M, Comeau MA, Abou Elela S, Ji X. Structure of a Eukaryotic RNase III Postcleavage Complex Reveals a Double-Ruler Mechanism for Substrate Selection. Mol Cell. 2014 Apr 2. pii: S1097-2765(14)00211-1. doi:, 10.1016/j.molcel.2014.03.006. PMID:24703949 doi:http://dx.doi.org/10.1016/j.molcel.2014.03.006

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