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4msx

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'''Unreleased structure'''
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{{STRUCTURE_4msx| PDB=4msx | SCENE= }}
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===Crystal structure of an essential yeast splicing factor===
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{{ABSTRACT_PUBMED_24681967}}
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The entry 4msx is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/SAD1_YEAST SAD1_YEAST]] Promotes the assembly of newly synthesized U4 snRNA into the U4/U6 snRNP particle. Required for splicing of pre-mRNA.<ref>PMID:10022888</ref>
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Authors: Hadjivassiliou, H., Guthrie, C., Rosenberg, O.S.
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==About this Structure==
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[[4msx]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MSX OCA].
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Description: Crystal structure of an essential yeast splicing factor
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==Reference==
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<ref group="xtra">PMID:024681967</ref><references group="xtra"/><references/>
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[[Category: Guthrie, C.]]
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[[Category: Hadjivassiliou, H.]]
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[[Category: Rosenberg, O S.]]
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[[Category: Deubiquitinase]]
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[[Category: Nuclear]]
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[[Category: Pre-mrna splicing]]
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[[Category: Pseudo-deubiquitinase]]
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[[Category: Spliceosome assembly]]
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[[Category: Splicing]]
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[[Category: Ubiquitin specific protease]]
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[[Category: Usp]]
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[[Category: Zinc finger ubiquitin binding protein]]
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[[Category: Znf-ubp]]

Revision as of 09:48, 16 April 2014

Template:STRUCTURE 4msx

Contents

Crystal structure of an essential yeast splicing factor

Template:ABSTRACT PUBMED 24681967

Function

[SAD1_YEAST] Promotes the assembly of newly synthesized U4 snRNA into the U4/U6 snRNP particle. Required for splicing of pre-mRNA.[1]

About this Structure

4msx is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Hadjivassiliou H, Rosenberg OS, Guthrie C. The crystal structure of S. cerevisiae Sad1, a catalytically inactive deubiquitinase that is broadly required for pre-mRNA splicing. RNA. 2014 Mar 28. PMID:24681967 doi:http://dx.doi.org/10.1261/rna.042838.113
  1. ↑ Lygerou Z, Christophides G, Seraphin B. A novel genetic screen for snRNP assembly factors in yeast identifies a conserved protein, Sad1p, also required for pre-mRNA splicing. Mol Cell Biol. 1999 Mar;19(3):2008-20. PMID:10022888

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