4bpm

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-	'''Unreleased structure'''	+	{{STRUCTURE_4bpm| PDB=4bpm | SCENE= }}
		+	===Crystal structure of a human integral membrane enzyme===
-	The entry 4bpm is ON HOLD until Paper Publication	+	==Function==
		+	[[http://www.uniprot.org/uniprot/PTGES_HUMAN PTGES_HUMAN]] Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).<ref>PMID:18682561</ref>
-	Authors: Li, D., Wang, M., Olieric, V., Caffrey, M.	+	==About this Structure==
		+	[[4bpm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BPM OCA].
-	Description: Crystal structure of a human integral membrane enzyme	+	==Reference==
		+	<references group="xtra"/><references/>
		+	[[Category: Prostaglandin-E synthase]]
		+	[[Category: Caffrey, M.]]
		+	[[Category: Li, D.]]
		+	[[Category: Olieric, V.]]
		+	[[Category: Wang, M.]]
		+	[[Category: Anomalous dispersion]]
		+	[[Category: Cancer]]
		+	[[Category: Drug target]]
		+	[[Category: In meso crystallization]]
		+	[[Category: Inflammation]]
		+	[[Category: Inhibitor]]
		+	[[Category: Isomerase]]
		+	[[Category: Leukotriene c4 synthase]]
		+	[[Category: Lipid metabolism]]
		+	[[Category: Mapag]]
		+	[[Category: Membrane protein]]
		+	[[Category: Membrane-associated proteins in eicosanoid and glutathione metabolism]]
		+	[[Category: Microcrystal]]
		+	[[Category: Mpges1]]
		+	[[Category: Pain]]
		+	[[Category: S-sad]]
		+	[[Category: Sulfur-sad]]

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Revision as of 09:58, 16 April 2014

Template:STRUCTURE 4bpm

Contents 1 Crystal structure of a human integral membrane enzyme 2 Function 3 About this Structure 4 Reference

Crystal structure of a human integral membrane enzyme

Function

[PTGES_HUMAN] Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).^[1]

About this Structure

4bpm is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

1. ↑ Jegerschold C, Pawelzik SC, Purhonen P, Bhakat P, Gheorghe KR, Gyobu N, Mitsuoka K, Morgenstern R, Jakobsson PJ, Hebert H. Structural basis for induced formation of the inflammatory mediator prostaglandin E2. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11110-5. Epub 2008 Aug 5. PMID:18682561 doi:0802894105