4k5b

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'''Unreleased structure'''
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{{STRUCTURE_4k5b| PDB=4k5b | SCENE= }}
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===Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W===
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The entry 4k5b is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/B2CL2_BOVIN B2CL2_BOVIN]] Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX (By similarity).
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Authors: Schilling, J., Schoeppe, J., Sauer, E., Plueckthun, A.
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==About this Structure==
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[[4k5b]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K5B OCA].
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Description: First crystal structure of anti-apoptotic BCL-W in its closed conformation
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[[Category: Plueckthun, A.]]
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[[Category: Sauer, E.]]
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[[Category: Schilling, J.]]
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[[Category: Schoeppe, J.]]
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[[Category: Anti-apoptotic bcl-2 family]]
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[[Category: Apoptosis]]
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[[Category: Bcl-w]]
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[[Category: Crystal structure]]
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[[Category: Darpin]]
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[[Category: Ligand binding-competent conformation]]

Revision as of 10:02, 16 April 2014

Template:STRUCTURE 4k5b

Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W

Function

[B2CL2_BOVIN] Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX (By similarity).

About this Structure

4k5b is a 4 chain structure. Full crystallographic information is available from OCA.

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OCA

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