4pwy

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Revision as of 08:34, 2 April 2014 (edit) OCA (Talk | contribs) m (Protected "4pwy" [edit=sysop:move=sysop]) ← Previous diff		Revision as of 10:12, 16 April 2014 (edit) (undo) OCA (Talk | contribs) Next diff →
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-	'''Unreleased structure'''	+	{{STRUCTURE_4pwy| PDB=4pwy | SCENE= }}
		+	===Crystal structure of a Calmodulin-lysine N-methyltransferase fragment===
-	The entry 4pwy is ON HOLD	+	==Disease==
		+	[[http://www.uniprot.org/uniprot/CMKMT_HUMAN CMKMT_HUMAN]] Atypical hypotonia - cystinuria syndrome;2p21 microdeletion syndrome without cystinuria;2p21 microdeletion syndrome.
-	Authors: Tempel, W., Hong, B.S., Walker, J.R., Li, Y., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Brown, P.J., Structural Genomics Consortium (SGC)	+	==Function==
		+	[[http://www.uniprot.org/uniprot/CMKMT_HUMAN CMKMT_HUMAN]] Catalyzes the trimethylation of 'Lys-116' in calmodulin.<ref>PMID:20975703</ref>
-	Description: Crystal structure of a Calmodulin-lysine N-methyltransferase fragment	+	==About this Structure==
		+	[[4pwy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PWY OCA].
		+
		+	==Reference==
		+	<references group="xtra"/><references/>
		+	[[Category: Calmodulin-lysine N-methyltransferase]]
		+	[[Category: Arrowsmith, C H.]]
		+	[[Category: Bountra, C.]]
		+	[[Category: Brown, P J.]]
		+	[[Category: Edwards, A M.]]
		+	[[Category: Hong, B S.]]
		+	[[Category: Li, Y.]]
		+	[[Category: SGC, Structural Genomics Consortium.]]
		+	[[Category: Tempel, W.]]
		+	[[Category: Walker, J R.]]
		+	[[Category: Methyl transferase]]
		+	[[Category: Sgc]]
		+	[[Category: Structural genomic]]
		+	[[Category: Structural genomics consortium]]
		+	[[Category: Transferase]]

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Revision as of 10:12, 16 April 2014

Template:STRUCTURE 4pwy

Contents 1 Crystal structure of a Calmodulin-lysine N-methyltransferase fragment 2 Disease 3 Function 4 About this Structure 5 Reference

Crystal structure of a Calmodulin-lysine N-methyltransferase fragment

Disease

[CMKMT_HUMAN] Atypical hypotonia - cystinuria syndrome;2p21 microdeletion syndrome without cystinuria;2p21 microdeletion syndrome.

Function

[CMKMT_HUMAN] Catalyzes the trimethylation of 'Lys-116' in calmodulin.^[1]

About this Structure

4pwy is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

1. ↑ Magnani R, Dirk LM, Trievel RC, Houtz RL. Calmodulin methyltransferase is an evolutionarily conserved enzyme that trimethylates Lys-115 in calmodulin. Nat Commun. 2010 Jul 27;1:43. doi: 10.1038/ncomms1044. PMID:20975703 doi:http://dx.doi.org/10.1038/ncomms1044