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1ph4
From Proteopedia
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{{STRUCTURE_1ph4| PDB=1ph4 | SCENE= }} | {{STRUCTURE_1ph4| PDB=1ph4 | SCENE= }} | ||
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===CRYSTAL STRUCTURE OF THE OXYTRICHA NOVA TELOMERE END-BINDING PROTEIN COMPLEXED WITH NONCOGNATE SSDNA GGGGTTTTGGCG=== | ===CRYSTAL STRUCTURE OF THE OXYTRICHA NOVA TELOMERE END-BINDING PROTEIN COMPLEXED WITH NONCOGNATE SSDNA GGGGTTTTGGCG=== | ||
| + | {{ABSTRACT_PUBMED_12912928}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/TEBB_OXYNO TEBB_OXYNO]] May function as protective capping of the single-stranded telomeric overhang. May also participate in telomere length regulation during DNA replication. Binds specifically to the T4G4-containing extension on the 3'strand and protects this region of the telomere from nuclease digestion and chemical modification. [[http://www.uniprot.org/uniprot/TEBA_OXYNO TEBA_OXYNO]] May function as protective capping of the single-stranded telomeric overhang. May also participate in telomere length regulation during DNA replication. Binds specifically to the T4G4-containing extension on the 3'strand and protects this region of the telomere from nuclease digestion and chemical modification. | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:012912928</ref><references group="xtra"/> | + | <ref group="xtra">PMID:012912928</ref><references group="xtra"/><references/> |
[[Category: Sterkiella nova]] | [[Category: Sterkiella nova]] | ||
[[Category: Schultz, S C.]] | [[Category: Schultz, S C.]] | ||
Revision as of 10:31, 16 April 2014
Contents |
CRYSTAL STRUCTURE OF THE OXYTRICHA NOVA TELOMERE END-BINDING PROTEIN COMPLEXED WITH NONCOGNATE SSDNA GGGGTTTTGGCG
Template:ABSTRACT PUBMED 12912928
Function
[TEBB_OXYNO] May function as protective capping of the single-stranded telomeric overhang. May also participate in telomere length regulation during DNA replication. Binds specifically to the T4G4-containing extension on the 3'strand and protects this region of the telomere from nuclease digestion and chemical modification. [TEBA_OXYNO] May function as protective capping of the single-stranded telomeric overhang. May also participate in telomere length regulation during DNA replication. Binds specifically to the T4G4-containing extension on the 3'strand and protects this region of the telomere from nuclease digestion and chemical modification.
About this Structure
1ph4 is a 5 chain structure with sequence from Sterkiella nova. Full crystallographic information is available from OCA.
Reference
- Theobald DL, Schultz SC. Nucleotide shuffling and ssDNA recognition in Oxytricha nova telomere end-binding protein complexes. EMBO J. 2003 Aug 15;22(16):4314-24. PMID:12912928 doi:http://dx.doi.org/10.1093/emboj/cdg415
