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1lc5

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[[Image:1lc5.png|left|200px]]
 
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{{STRUCTURE_1lc5| PDB=1lc5 | SCENE= }}
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===Crystal Structure of L-Threonine-O-3-phosphate Decarboxylase from S. enterica in its apo state===
===Crystal Structure of L-Threonine-O-3-phosphate Decarboxylase from S. enterica in its apo state===
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{{ABSTRACT_PUBMED_12119022}}
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==Function==
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[[http://www.uniprot.org/uniprot/COBD_SALTY COBD_SALTY]] Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.<ref>PMID:9446573</ref>
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{{ABSTRACT_PUBMED_12119022}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:012119022</ref><references group="xtra"/>
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<ref group="xtra">PMID:012119022</ref><references group="xtra"/><references/>
[[Category: Salmonella enterica]]
[[Category: Salmonella enterica]]
[[Category: Cheong, C G.]]
[[Category: Cheong, C G.]]

Revision as of 10:33, 16 April 2014

Template:STRUCTURE 1lc5

Contents

Crystal Structure of L-Threonine-O-3-phosphate Decarboxylase from S. enterica in its apo state

Template:ABSTRACT PUBMED 12119022

Function

[COBD_SALTY] Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.[1]

About this Structure

1lc5 is a 1 chain structure with sequence from Salmonella enterica. Full crystallographic information is available from OCA.

Reference

  • Cheong CG, Escalante-Semerena JC, Rayment I. Structural studies of the L-threonine-O-3-phosphate decarboxylase (CobD) enzyme from Salmonella enterica: the apo, substrate, and product-aldimine complexes. Biochemistry. 2002 Jul 23;41(29):9079-89. PMID:12119022
  1. ↑ Brushaber KR, O'Toole GA, Escalante-Semerena JC. CobD, a novel enzyme with L-threonine-O-3-phosphate decarboxylase activity, is responsible for the synthesis of (R)-1-amino-2-propanol O-2-phosphate, a proposed new intermediate in cobalamin biosynthesis in Salmonella typhimurium LT2. J Biol Chem. 1998 Jan 30;273(5):2684-91. PMID:9446573

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