1iic
From Proteopedia
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{{STRUCTURE_1iic| PDB=1iic | SCENE= }} | {{STRUCTURE_1iic| PDB=1iic | SCENE= }} | ||
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===Crystal Structure of Saccharomyces cerevisiae N-myristoyltransferase with Bound MyristoylCoA=== | ===Crystal Structure of Saccharomyces cerevisiae N-myristoyltransferase with Bound MyristoylCoA=== | ||
| + | {{ABSTRACT_PUBMED_11371195}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/NMT_YEAST NMT_YEAST]] Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins. Substrate specificity requires an N-terminal glycine in the nascent polypeptide substrates. Uncharged amino acids are preferred at position 2 while neutral residues are favored at positions 3 and 4. Ser is present at position 5 in almost all known N-myristoyl proteins and Lys is commonly encountered at postion 6. | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:011371195</ref><references group="xtra"/> | + | <ref group="xtra">PMID:011371195</ref><references group="xtra"/><references/> |
[[Category: Glycylpeptide N-tetradecanoyltransferase]] | [[Category: Glycylpeptide N-tetradecanoyltransferase]] | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
Revision as of 10:40, 16 April 2014
Contents |
Crystal Structure of Saccharomyces cerevisiae N-myristoyltransferase with Bound MyristoylCoA
Template:ABSTRACT PUBMED 11371195
Function
[NMT_YEAST] Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins. Substrate specificity requires an N-terminal glycine in the nascent polypeptide substrates. Uncharged amino acids are preferred at position 2 while neutral residues are favored at positions 3 and 4. Ser is present at position 5 in almost all known N-myristoyl proteins and Lys is commonly encountered at postion 6.
About this Structure
1iic is a 2 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
Reference
- Farazi TA, Waksman G, Gordon JI. Structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoylCoA and peptide provide insights about substrate recognition and catalysis. Biochemistry. 2001 May 29;40(21):6335-43. PMID:11371195
