1f7b

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[[Image:1f7b.png|left|200px]]
 
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{{STRUCTURE_1f7b| PDB=1f7b | SCENE= }}
{{STRUCTURE_1f7b| PDB=1f7b | SCENE= }}
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===CRYSTAL STRUCTURE ANALYSIS OF N-ACETYLNEURAMINATE LYASE FROM HAEMOPHILUS INFLUENZAE: CRYSTAL FORM II IN COMPLEX WITH 4-OXO-SIALIC ACID===
===CRYSTAL STRUCTURE ANALYSIS OF N-ACETYLNEURAMINATE LYASE FROM HAEMOPHILUS INFLUENZAE: CRYSTAL FORM II IN COMPLEX WITH 4-OXO-SIALIC ACID===
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{{ABSTRACT_PUBMED_11031117}}
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==Function==
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[[http://www.uniprot.org/uniprot/NANA_HAEIN NANA_HAEIN]] Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate.
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{{ABSTRACT_PUBMED_11031117}}
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==About this Structure==
==About this Structure==
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1F7B is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F7B OCA].
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[[1f7b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F7B OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:11031117</ref><references group="xtra"/>
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<ref group="xtra">PMID:011031117</ref><references group="xtra"/><references/>
[[Category: Haemophilus influenzae]]
[[Category: Haemophilus influenzae]]
[[Category: N-acetylneuraminate lyase]]
[[Category: N-acetylneuraminate lyase]]
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[[Category: Smith, B J.]]
[[Category: Smith, B J.]]
[[Category: Beta barrel]]
[[Category: Beta barrel]]
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[[Category: Lyase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:48:59 2009''
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Revision as of 10:47, 16 April 2014

Template:STRUCTURE 1f7b

Contents

CRYSTAL STRUCTURE ANALYSIS OF N-ACETYLNEURAMINATE LYASE FROM HAEMOPHILUS INFLUENZAE: CRYSTAL FORM II IN COMPLEX WITH 4-OXO-SIALIC ACID

Template:ABSTRACT PUBMED 11031117

Function

[NANA_HAEIN] Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate.

About this Structure

1f7b is a 2 chain structure with sequence from Haemophilus influenzae. Full crystallographic information is available from OCA.

Reference

  • Barbosa JA, Smith BJ, DeGori R, Ooi HC, Marcuccio SM, Campi EM, Jackson WR, Brossmer R, Sommer M, Lawrence MC. Active site modulation in the N-acetylneuraminate lyase sub-family as revealed by the structure of the inhibitor-complexed Haemophilus influenzae enzyme. J Mol Biol. 2000 Oct 27;303(3):405-21. PMID:11031117 doi:http://dx.doi.org/10.1006/jmbi.2000.4138

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