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1kny
From Proteopedia
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{{STRUCTURE_1kny| PDB=1kny | SCENE= }} | {{STRUCTURE_1kny| PDB=1kny | SCENE= }} | ||
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===KANAMYCIN NUCLEOTIDYLTRANSFERASE=== | ===KANAMYCIN NUCLEOTIDYLTRANSFERASE=== | ||
| + | {{ABSTRACT_PUBMED_7577914}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/KANU_STAAU KANU_STAAU]] Inactivates the antibiotic kanamycin by catalyzing the transfer of a nucleotidyl group from nucleoside triphosphates such as ATP to the 4'-hydroxyl group of the aminoglycoside. | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:007577914</ref><references group="xtra"/> | + | <ref group="xtra">PMID:007577914</ref><references group="xtra"/><references/> |
[[Category: Aminoglycoside Antibiotics]] | [[Category: Aminoglycoside Antibiotics]] | ||
[[Category: RCSB PDB Molecule of the Month]] | [[Category: RCSB PDB Molecule of the Month]] | ||
Revision as of 10:59, 16 April 2014
Contents |
KANAMYCIN NUCLEOTIDYLTRANSFERASE
Template:ABSTRACT PUBMED 7577914
Function
[KANU_STAAU] Inactivates the antibiotic kanamycin by catalyzing the transfer of a nucleotidyl group from nucleoside triphosphates such as ATP to the 4'-hydroxyl group of the aminoglycoside.
About this Structure
1kny is a 2 chain structure with sequence from Staphylococcus aureus. The February 2012 RCSB PDB Molecule of the Month feature on Aminoglycoside Antibiotics by David Goodsell is 10.2210/rcsb_pdb/mom_2012_2. Full crystallographic information is available from OCA.
Reference
- Pedersen LC, Benning MM, Holden HM. Structural investigation of the antibiotic and ATP-binding sites in kanamycin nucleotidyltransferase. Biochemistry. 1995 Oct 17;34(41):13305-11. PMID:7577914
