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1jg3

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[[Image:1jg3.png|left|200px]]
 
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{{STRUCTURE_1jg3| PDB=1jg3 | SCENE= }}
{{STRUCTURE_1jg3| PDB=1jg3 | SCENE= }}
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===Crystal Structure of L-isoaspartyl (D-aspartyl) O-methyltransferase with adenosine & VYP(ISP)HA substrate===
===Crystal Structure of L-isoaspartyl (D-aspartyl) O-methyltransferase with adenosine & VYP(ISP)HA substrate===
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{{ABSTRACT_PUBMED_11700066}}
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==Function==
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[[http://www.uniprot.org/uniprot/PIMT_PYRFU PIMT_PYRFU]] Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins (By similarity).
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{{ABSTRACT_PUBMED_11700066}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:011700066</ref><references group="xtra"/>
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<ref group="xtra">PMID:011700066</ref><references group="xtra"/><references/>
[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
[[Category: Boutz, D.]]
[[Category: Boutz, D.]]

Revision as of 11:02, 16 April 2014

Template:STRUCTURE 1jg3

Contents

Crystal Structure of L-isoaspartyl (D-aspartyl) O-methyltransferase with adenosine & VYP(ISP)HA substrate

Template:ABSTRACT PUBMED 11700066

Function

[PIMT_PYRFU] Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins (By similarity).

About this Structure

1jg3 is a 4 chain structure with sequence from Pyrococcus furiosus. Full crystallographic information is available from OCA.

Reference

  • Griffith SC, Sawaya MR, Boutz DR, Thapar N, Katz JE, Clarke S, Yeates TO. Crystal structure of a protein repair methyltransferase from Pyrococcus furiosus with its L-isoaspartyl peptide substrate. J Mol Biol. 2001 Nov 9;313(5):1103-16. PMID:11700066 doi:10.1006/jmbi.2001.5095

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