1f74

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1f74" [edit=sysop:move=sysop])

Revision as of 11:03, 16 April 2014

Template:STRUCTURE 1f74

Contents

CRYSTAL STRUCTURE ANALYSIS OF N-ACETYLNEURAMINATE LYASE FROM HAEMOPHILUS INFLUENZAE: CRYSTAL FORM II COMPLEXED WITH 4-DEOXY-SIALIC ACID

Template:ABSTRACT PUBMED 11031117

Function

[NANA_HAEIN] Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate.

About this Structure

1f74 is a 2 chain structure with sequence from Haemophilus influenzae. Full crystallographic information is available from OCA.

Reference

  • Barbosa JA, Smith BJ, DeGori R, Ooi HC, Marcuccio SM, Campi EM, Jackson WR, Brossmer R, Sommer M, Lawrence MC. Active site modulation in the N-acetylneuraminate lyase sub-family as revealed by the structure of the inhibitor-complexed Haemophilus influenzae enzyme. J Mol Biol. 2000 Oct 27;303(3):405-21. PMID:11031117 doi:http://dx.doi.org/10.1006/jmbi.2000.4138

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1f74"
Personal tools