This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4n1b
From Proteopedia
| Line 4: | Line 4: | ||
==About this Structure== | ==About this Structure== | ||
| - | [[4n1b]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N1B OCA]. | + | [[4n1b]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N1B OCA]. |
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:024504667</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:024504667</ref><references group="xtra"/><references/> | ||
| + | [[Category: Human]] | ||
[[Category: Albrecht, C.]] | [[Category: Albrecht, C.]] | ||
[[Category: Barker, J.]] | [[Category: Barker, J.]] | ||
Revision as of 06:42, 23 April 2014
STRUCTURE OF KEAP1 KELCH DOMAIN WITH(1S,2R)-2-[(1S)-1-[(1-oxo-2,3-dihydro-1H-isoindol-2-Yl)methyl]-1,2,3,4-tetrahydroisoquinoline-2-Carbonyl]cyclohexane-1-carboxylic acid
Template:ABSTRACT PUBMED 24504667
About this Structure
4n1b is a 3 chain structure with sequence from Human. Full crystallographic information is available from OCA.
Reference
- Jnoff E, Albrecht C, Barker JJ, Barker O, Beaumont E, Bromidge S, Brookfield F, Brooks M, Bubert C, Ceska T, Corden V, Dawson G, Duclos S, Fryatt T, Genicot C, Jigorel E, Kwong J, Maghames R, Mushi I, Pike R, Sands ZA, Smith MA, Stimson CC, Courade JP. Binding Mode and Structure-Activity Relationships around Direct Inhibitors of the Nrf2-Keap1 Complex. ChemMedChem. 2014 Feb 6. doi: 10.1002/cmdc.201300525. PMID:24504667 doi:http://dx.doi.org/10.1002/cmdc.201300525
Categories: Human | Albrecht, C. | Barker, J. | Barker, O. | Beaumont, E. | Bromidge, S. | Brookfield, F. | Brooks, M. | Courade, J P. | Duclos, S. | Fryatt, T. | Jnoff, E. | Kwong, J. | Smith, M A. | Beta-propeller | Cytosol | Kelch domain | Kelch repeat motif | Nrf2 | Protein-small molecule complex | Replacement soaking | Small molecular binding | Stress sensor | Transcription-inhibitor complex
