1vbj
From Proteopedia
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{{STRUCTURE_1vbj| PDB=1vbj | SCENE= }} | {{STRUCTURE_1vbj| PDB=1vbj | SCENE= }} | ||
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===The crystal structure of prostaglandin F synthase from Trypanosoma brucei=== | ===The crystal structure of prostaglandin F synthase from Trypanosoma brucei=== | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/Q9GV41_9TRYP Q9GV41_9TRYP]] Catalyzes the NADP-dependent formation of prostaglandin F2-alpha from prostaglandin H2. Has also aldo/ketoreductase activity towards the synthetic substrates 9,10-phenanthrenequinone and p-nitrobenzaldehyde. | |
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==About this Structure== | ==About this Structure== | ||
[[1vbj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VBJ OCA]. | [[1vbj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VBJ OCA]. | ||
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| + | ==See Also== | ||
| + | *[[Prostaglandin F synthase|Prostaglandin F synthase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:015845552</ref><references group="xtra"/> | + | <ref group="xtra">PMID:015845552</ref><references group="xtra"/><references/> |
[[Category: Prostaglandin-F synthase]] | [[Category: Prostaglandin-F synthase]] | ||
[[Category: Trypanosoma brucei]] | [[Category: Trypanosoma brucei]] | ||
Revision as of 08:15, 23 April 2014
Contents |
The crystal structure of prostaglandin F synthase from Trypanosoma brucei
Function
[Q9GV41_9TRYP] Catalyzes the NADP-dependent formation of prostaglandin F2-alpha from prostaglandin H2. Has also aldo/ketoreductase activity towards the synthetic substrates 9,10-phenanthrenequinone and p-nitrobenzaldehyde.
About this Structure
1vbj is a 2 chain structure with sequence from Trypanosoma brucei. Full crystallographic information is available from OCA.
See Also
Reference
- Kilunga KB, Inoue T, Okano Y, Kabututu Z, Martin SK, Lazarus M, Duszenko M, Sumii Y, Kusakari Y, Matsumura H, Kai Y, Sugiyama S, Inaka K, Inui T, Urade Y. Structural and mutational analysis of Trypanosoma brucei prostaglandin H2 reductase provides insight into the catalytic mechanism of aldo-ketoreductases. J Biol Chem. 2005 Jul 15;280(28):26371-82. Epub 2005 Apr 21. PMID:15845552 doi:10.1074/jbc.M413884200
