1yde

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[[Image:1yde.png|left|200px]]
 
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{{STRUCTURE_1yde| PDB=1yde | SCENE= }}
{{STRUCTURE_1yde| PDB=1yde | SCENE= }}
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===Crystal Structure of Human Retinal Short-Chain Dehydrogenase/Reductase 3===
===Crystal Structure of Human Retinal Short-Chain Dehydrogenase/Reductase 3===
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{{ABSTRACT_PUBMED_17067289}}
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==Function==
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[[http://www.uniprot.org/uniprot/DHR10_HUMAN DHR10_HUMAN]] Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).<ref>PMID:17067289</ref>
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{{ABSTRACT_PUBMED_17067289}}
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==About this Structure==
==About this Structure==
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[[1yde]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YDE OCA].
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[[1yde]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YDE OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:017067289</ref><references group="xtra"/>
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<ref group="xtra">PMID:017067289</ref><references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Arrowsmith, C.]]
[[Category: Arrowsmith, C.]]
[[Category: Bunkozci, G.]]
[[Category: Bunkozci, G.]]

Revision as of 08:21, 23 April 2014

Template:STRUCTURE 1yde

Contents

Crystal Structure of Human Retinal Short-Chain Dehydrogenase/Reductase 3

Template:ABSTRACT PUBMED 17067289

Function

[DHR10_HUMAN] Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).[1]

About this Structure

1yde is a 16 chain structure with sequence from Human. Full crystallographic information is available from OCA.

Reference

  • Lukacik P, Keller B, Bunkoczi G, Kavanagh KL, Lee WH, Adamski J, Oppermann U. Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity. Biochem J. 2007 Mar 15;402(3):419-27. PMID:17067289 doi:BJ20061319
  1. ↑ Lukacik P, Keller B, Bunkoczi G, Kavanagh KL, Lee WH, Adamski J, Oppermann U. Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity. Biochem J. 2007 Mar 15;402(3):419-27. PMID:17067289 doi:BJ20061319

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