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1szu

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[[Image:1szu.png|left|200px]]
 
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{{STRUCTURE_1szu| PDB=1szu | SCENE= }}
{{STRUCTURE_1szu| PDB=1szu | SCENE= }}
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===The structure of gamma-aminobutyrate aminotransferase mutant: V241A===
===The structure of gamma-aminobutyrate aminotransferase mutant: V241A===
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{{ABSTRACT_PUBMED_15723541}}
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==Function==
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[[http://www.uniprot.org/uniprot/GABT_ECOLI GABT_ECOLI]] Catalyzes the transfer of the amino group from gamma-aminobutyrate (GABA) to alpha-ketoglutarate (KG) to yield succinic semialdehyde (SSA).<ref>PMID:20639325</ref>
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{{ABSTRACT_PUBMED_15723541}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:015723541</ref><references group="xtra"/>
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<ref group="xtra">PMID:015723541</ref><references group="xtra"/><references/>
[[Category: 4-aminobutyrate transaminase]]
[[Category: 4-aminobutyrate transaminase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]

Revision as of 08:28, 23 April 2014

Template:STRUCTURE 1szu

Contents

The structure of gamma-aminobutyrate aminotransferase mutant: V241A

Template:ABSTRACT PUBMED 15723541

Function

[GABT_ECOLI] Catalyzes the transfer of the amino group from gamma-aminobutyrate (GABA) to alpha-ketoglutarate (KG) to yield succinic semialdehyde (SSA).[1]

About this Structure

1szu is a 4 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  • Liu W, Peterson PE, Langston JA, Jin X, Zhou X, Fisher AJ, Toney MD. Kinetic and crystallographic analysis of active site mutants of Escherichia coli gamma-aminobutyrate aminotransferase. Biochemistry. 2005 Mar 1;44(8):2982-92. PMID:15723541 doi:http://dx.doi.org/10.1021/bi048657a
  1. ↑ Kurihara S, Kato K, Asada K, Kumagai H, Suzuki H. A putrescine-inducible pathway comprising PuuE-YneI in which gamma-aminobutyrate is degraded into succinate in Escherichia coli K-12. J Bacteriol. 2010 Sep;192(18):4582-91. doi: 10.1128/JB.00308-10. Epub 2010 Jul, 16. PMID:20639325 doi:http://dx.doi.org/10.1128/JB.00308-10

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OCA

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