2b0u

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[[Image:2b0u.png|left|200px]]
 
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{{STRUCTURE_2b0u| PDB=2b0u | SCENE= }}
{{STRUCTURE_2b0u| PDB=2b0u | SCENE= }}
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===The Structure of the Follistatin:Activin Complex===
===The Structure of the Follistatin:Activin Complex===
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{{ABSTRACT_PUBMED_16198295}}
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==Function==
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[[http://www.uniprot.org/uniprot/INHBA_HUMAN INHBA_HUMAN]] Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. [[http://www.uniprot.org/uniprot/FST_HUMAN FST_HUMAN]] Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).
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{{ABSTRACT_PUBMED_16198295}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:016198295</ref><references group="xtra"/>
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<ref group="xtra">PMID:016198295</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Cook, R W.]]
[[Category: Cook, R W.]]

Revision as of 08:50, 23 April 2014

Template:STRUCTURE 2b0u

Contents

The Structure of the Follistatin:Activin Complex

Template:ABSTRACT PUBMED 16198295

Function

[INHBA_HUMAN] Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. [FST_HUMAN] Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).

About this Structure

2b0u is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Proteopedia Page Contributors and Editors (what is this?)

OCA

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