1z5p

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1z5p" [edit=sysop:move=sysop])
Line 1: Line 1:
-
[[Image:1z5p.png|left|200px]]
 
- 
-
<!--
 
-
The line below this paragraph, containing "STRUCTURE_1z5p", creates the "Structure Box" on the page.
 
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
 
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
 
-
or leave the SCENE parameter empty for the default display.
 
-
-->
 
{{STRUCTURE_1z5p| PDB=1z5p | SCENE= }}
{{STRUCTURE_1z5p| PDB=1z5p | SCENE= }}
- 
===Crystal structure of MTA/AdoHcy nucleosidase with a ligand-free purine binding site===
===Crystal structure of MTA/AdoHcy nucleosidase with a ligand-free purine binding site===
 +
{{ABSTRACT_PUBMED_16109423}}
-
 
+
==Function==
-
<!--
+
[[http://www.uniprot.org/uniprot/MTNN_ECOLI MTNN_ECOLI]] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Can also use 5'-isobutylthioadenosine, 5'-n-butylthioadenosine, S-adenosyl-D-homocysteine, decarboxylated adenosylhomocysteine, deaminated adenosylhomocysteine and S-2-aza-adenosylhomocysteine as substrates.[HAMAP-Rule:MF_01684]
-
The line below this paragraph, {{ABSTRACT_PUBMED_16109423}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 16109423 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_16109423}}
+
==About this Structure==
==About this Structure==
Line 22: Line 10:
==Reference==
==Reference==
-
<ref group="xtra">PMID:016109423</ref><references group="xtra"/>
+
<ref group="xtra">PMID:016109423</ref><references group="xtra"/><references/>
[[Category: Adenosylhomocysteine nucleosidase]]
[[Category: Adenosylhomocysteine nucleosidase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]

Revision as of 08:53, 23 April 2014

Template:STRUCTURE 1z5p

Contents

Crystal structure of MTA/AdoHcy nucleosidase with a ligand-free purine binding site

Template:ABSTRACT PUBMED 16109423

Function

[MTNN_ECOLI] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Can also use 5'-isobutylthioadenosine, 5'-n-butylthioadenosine, S-adenosyl-D-homocysteine, decarboxylated adenosylhomocysteine, deaminated adenosylhomocysteine and S-2-aza-adenosylhomocysteine as substrates.[HAMAP-Rule:MF_01684]

About this Structure

1z5p is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  • Lee JE, Smith GD, Horvatin C, Huang DJ, Cornell KA, Riscoe MK, Howell PL. Structural snapshots of MTA/AdoHcy nucleosidase along the reaction coordinate provide insights into enzyme and nucleoside flexibility during catalysis. J Mol Biol. 2005 Sep 23;352(3):559-74. PMID:16109423 doi:http://dx.doi.org/10.1016/j.jmb.2005.07.027

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1z5p"
Personal tools