4kga
From Proteopedia
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| - | ''' | + | ==Crystal structure of kallikrein-related peptidase 4== |
| - | + | <StructureSection load='4kga' size='340' side='right' caption='[[4kga]], [[Resolution|resolution]] 2.32Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | [[4kga]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KGA OCA]. <br> | |
| - | + | <b>Related:</b> [[2bdg|2bdg]], [[2bdi|2bdi]], [[2bdh|2bdh]], [[4kel|4kel]], [[4k8y|4k8y]], [[4k1e|4k1e]]<br> | |
| - | + | <b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br> | |
| - | + | == Disease == | |
| + | [[http://www.uniprot.org/uniprot/KLK4_HUMAN KLK4_HUMAN]] Defects in KLK4 are the cause of amelogenesis imperfecta hypomaturation type 2A1 (AI2A1) [MIM:[http://omim.org/entry/204700 204700]]. AI2A1 is an autosomal recessive defect of enamel formation. The disorder involves both primary and secondary dentitions. The teeth have a shiny agar jelly appearance and the enamel is softer than normal. Brown pigment is present in middle layers of enamel.<ref>PMID:15235027</ref> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/KLK4_HUMAN KLK4_HUMAN]] Involved in enamel formation.<ref>PMID:15235027</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Buckle, A M.]] | ||
| + | [[Category: Harris, J M.]] | ||
| + | [[Category: Ilyichova, O V.]] | ||
| + | [[Category: Sit, K C.]] | ||
| + | [[Category: Swedberg, J E.]] | ||
| + | [[Category: Veer, S J.de.]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Kallikrein-4]] | ||
| + | [[Category: Klk4]] | ||
| + | [[Category: Protease]] | ||
| + | [[Category: Serine protease]] | ||
Revision as of 07:59, 30 April 2014
Crystal structure of kallikrein-related peptidase 4
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