2l2r

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2l2r.png|left|200px]]
+
==Helical hairpin structure of a novel antimicrobial peptide EcAMP1 from seeds of barnyard grass (Echinochloa crus-galli)==
 +
<StructureSection load='2l2r' size='340' side='right' caption='[[2l2r]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
 +
== Structural highlights ==
 +
[[2l2r]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Barnyard_grass Barnyard grass]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L2R OCA]. <br>
 +
<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
 +
== Publication Abstract from PubMed ==
 +
This study presents purification, activity characterization, and (1)H NMR study of the novel antifungal peptide EcAMP1 from kernels of barnyard grass Echinochloa crus-galli. The peptide adopts a disulfide-stabilized alpha-helical hairpin structure in aqueous solution and thus represents a novel fold among naturally occurring antimicrobial peptides. Micromolar concentrations of EcAMP1 were shown to inhibit growth of several fungal phytopathogens. Confocal microscopy revealed intensive EcAMP1 binding to the surface of fungal conidia followed by internalization and accumulation in the cytoplasm without disturbance of membrane integrity. Close spatial structure similarity between EcAMP1, the trypsin inhibitor VhTI from seeds of Veronica hederifolia, and some scorpion and cone snail toxins suggests natural elaboration of different functions on a common fold.
-
<!--
+
Disulfide-stabilized Helical Hairpin Structure and Activity of a Novel Antifungal Peptide EcAMP1 from Seeds of Barnyard Grass (Echinochloa crus-galli).,Nolde SB, Vassilevski AA, Rogozhin EA, Barinov NA, Balashova TA, Samsonova OV, Baranov YV, Feofanov AV, Egorov TA, Arseniev AS, Grishin EV J Biol Chem. 2011 Jul 15;286(28):25145-53. Epub 2011 May 11. PMID:21561864<ref>PMID:21561864</ref>
-
The line below this paragraph, containing "STRUCTURE_2l2r", creates the "Structure Box" on the page.
+
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
-
or leave the SCENE parameter empty for the default display.
+
-
-->
+
-
{{STRUCTURE_2l2r| PDB=2l2r | SCENE= }}
+
-
===Helical hairpin structure of a novel antimicrobial peptide EcAMP1 from seeds of barnyard grass (Echinochloa crus-galli)===
+
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-
 
+
== References ==
-
 
+
<references/>
-
<!--
+
__TOC__
-
The line below this paragraph, {{ABSTRACT_PUBMED_21561864}}, adds the Publication Abstract to the page
+
</StructureSection>
-
(as it appears on PubMed at http://www.pubmed.gov), where 21561864 is the PubMed ID number.
+
[[Category: Barnyard grass]]
-
-->
+
-
{{ABSTRACT_PUBMED_21561864}}
+
-
 
+
-
==About this Structure==
+
-
[[2l2r]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Echinochloa_crus-galli Echinochloa crus-galli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L2R OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:021561864</ref><references group="xtra"/>
+
-
[[Category: Echinochloa crus-galli]]
+
[[Category: Arseniev, A S.]]
[[Category: Arseniev, A S.]]
[[Category: Balashova, T A.]]
[[Category: Balashova, T A.]]

Revision as of 08:35, 30 April 2014

Helical hairpin structure of a novel antimicrobial peptide EcAMP1 from seeds of barnyard grass (Echinochloa crus-galli)

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2l2r"
Personal tools