2l7m

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[[Image:2l7m.jpg|left|200px]]
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==Solution Structure of the Pitx2 Homeodomain R24H mutant==
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<StructureSection load='2l7m' size='340' side='right' caption='[[2l7m]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<!--
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== Structural highlights ==
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The line below this paragraph, containing "STRUCTURE_2l7m", creates the "Structure Box" on the page.
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[[2l7m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L7M OCA]. <br>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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<b>Related:</b> [[2l7f|2l7f]]<br>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
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or leave the SCENE parameter empty for the default display.
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== Disease ==
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[[http://www.uniprot.org/uniprot/PITX2_HUMAN PITX2_HUMAN]] Peters anomaly;Axenfeld anomaly;Rieger anomaly;Ring dermoid of cornea;Axenfeld-Rieger syndrome. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
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{{STRUCTURE_2l7m| PDB=2l7m | SCENE= }}
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== Function ==
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[[http://www.uniprot.org/uniprot/PITX2_HUMAN PITX2_HUMAN]] Controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, exerts a role in the expansion of muscle progenitors. May play a role in the proper localization of asymmetric organs such as the heart and stomach. Isoform PTX2C is involved in left-right asymmetry the developing embryo (By similarity).
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===Solution Structure of the Pitx2 Homeodomain R24H mutant===
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== References ==
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<references/>
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__TOC__
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==About this Structure==
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</StructureSection>
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[[2l7m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L7M OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Baird-Titus, J M.]]
[[Category: Baird-Titus, J M.]]

Revision as of 08:40, 30 April 2014

Solution Structure of the Pitx2 Homeodomain R24H mutant

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