This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2lb7

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2lb7.png|left|200px]]
+
==Hevein-type Antifungal Peptide with a Unique 10-Cysteine Motif==
 +
<StructureSection load='2lb7' size='340' side='right' caption='[[2lb7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
 +
== Structural highlights ==
 +
[[2lb7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Triticum_kiharae Triticum kiharae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LB7 OCA]. <br>
 +
<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
 +
== Publication Abstract from PubMed ==
 +
Hevein, a well-studied lectin from the rubber tree Hevea brasiliensis, is the title representative of a broad family of chitin-binding polypeptides. WAMP-1a, a peptide isolated from the wheat Triticum kiharae, shares considerable similarity with hevein. The peptide possesses antifungal, antibacterial activity and is thought to play an important role in the defense system of wheat. Importantly, it features a substitution of the conserved serine residue to glycine reducing its carbohydrate-binding capacity. We used NMR spectroscopy to derive the spatial structure of WAMP-1a in aqueous solution. Notably, the mutation was found to strengthen amphiphilicity of the molecule, associated with its mode of action, an indication of the hevein domain multi-functionality. Both primary and tertiary structure of WAMP-1a suggest its evolutionary origin from the hevein domain of plant chitinases.
-
<!--
+
Solution structure of a defense peptide from wheat with a 10-cysteine motif.,Dubovskii PV, Vassilevski AA, Slavokhotova AA, Odintsova TI, Grishin EV, Egorov TA, Arseniev AS Biochem Biophys Res Commun. 2011 Jul 22;411(1):14-8. Epub 2011 Jun 14. PMID:21704019<ref>PMID:21704019</ref>
-
The line below this paragraph, containing "STRUCTURE_2lb7", creates the "Structure Box" on the page.
+
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
-
or leave the SCENE parameter empty for the default display.
+
-
-->
+
-
{{STRUCTURE_2lb7| PDB=2lb7 | SCENE= }}
+
-
===Hevein-type Antifungal Peptide with a Unique 10-Cysteine Motif===
+
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-
 
+
== References ==
-
 
+
<references/>
-
<!--
+
__TOC__
-
The line below this paragraph, {{ABSTRACT_PUBMED_21704019}}, adds the Publication Abstract to the page
+
</StructureSection>
-
(as it appears on PubMed at http://www.pubmed.gov), where 21704019 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_21704019}}
+
-
 
+
-
==About this Structure==
+
-
[[2lb7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Triticum_kiharae Triticum kiharae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LB7 OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:021704019</ref><ref group="xtra">PMID:019583772</ref><references group="xtra"/>
+
[[Category: Triticum kiharae]]
[[Category: Triticum kiharae]]
[[Category: Arseniev, A S.]]
[[Category: Arseniev, A S.]]

Revision as of 08:42, 30 April 2014

Hevein-type Antifungal Peptide with a Unique 10-Cysteine Motif

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2lb7"
Personal tools