4fxy

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{{STRUCTURE_4fxy| PDB=4fxy | SCENE= }}
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==Crystal structure of rat neurolysin with bound pyrazolidin inhibitor==
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===Crystal structure of rat neurolysin with bound pyrazolidin inhibitor===
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<StructureSection load='4fxy' size='340' side='right' caption='[[4fxy]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[4fxy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FXY OCA]. <br>
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[[http://www.uniprot.org/uniprot/NEUL_RAT NEUL_RAT]] Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A.
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0W2:1-{(2S)-1-[(3R)-3-(2-CHLOROPHENYL)-2-(2-FLUOROPHENYL)PYRAZOLIDIN-1-YL]-1-OXOPROPAN-2-YL}-3-[(1R,3S,5R,7R)-TRICYCLO[3.3.1.1~3,7~]DEC-2-YL]UREA'>0W2</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1i1i|1i1i]], [[2o3e|2o3e]]</td></tr>
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==About this Structure==
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Nln ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
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[[4fxy]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FXY OCA].
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fxy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fxy RCSB], [http://www.ebi.ac.uk/pdbsum/4fxy PDBsum]</span></td></tr>
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<table>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Buffalo rat]]
[[Category: Neurolysin]]
[[Category: Neurolysin]]
[[Category: Hines, C S.]]
[[Category: Hines, C S.]]

Revision as of 06:41, 7 May 2014

Crystal structure of rat neurolysin with bound pyrazolidin inhibitor

4fxy, resolution 2.80Å

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