4jxs

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'''Unreleased structure'''
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==X-ray crystal structure of AmpC beta-lactamase from E. coli in complex with a non-covalent inhibitor 3-[(4-CARBOXYBENZYL)SULFAMOYL]THIOPHENE-2-CARBOXYLIC ACID (compound 4)==
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<StructureSection load='4jxs' size='340' side='right' caption='[[4jxs]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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The entry 4jxs is ON HOLD until Jul 02 2015
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4jxs]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JXS OCA]. <br>
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Authors: Powers, R.A., Hendershot, J.M.
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=18U:3-[(4-CARBOXYBENZYL)SULFAMOYL]THIOPHENE-2-CARBOXYLIC+ACID'>18U</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1l2s|1l2s]], [[1xgi|1xgi]], [[1xgj|1xgj]], [[4jxv|4jxv]], [[4jxw|4jxw]]</td></tr>
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Description:
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jxs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jxs RCSB], [http://www.ebi.ac.uk/pdbsum/4jxs PDBsum]</span></td></tr>
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<table>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Beta-lactamase]]
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[[Category: Hendershot, J M.]]
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[[Category: Powers, R A.]]
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[[Category: Beta-lactamase]]
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[[Category: Beta-lactamase inhibitor complex]]
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[[Category: Cephalosporinase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Serine hydrolase]]

Revision as of 08:19, 7 May 2014

X-ray crystal structure of AmpC beta-lactamase from E. coli in complex with a non-covalent inhibitor 3-[(4-CARBOXYBENZYL)SULFAMOYL]THIOPHENE-2-CARBOXYLIC ACID (compound 4)

4jxs, resolution 1.90Å

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