User:Jaakko Itkonen

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and like many other cytokines, is folded
and like many other cytokines, is folded
into a four α-helix bundle.
into a four α-helix bundle.
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Fig. 1 X-ray structure of a truncated form of hCNTF (2-187)
Fig. 1 X-ray structure of a truncated form of hCNTF (2-187)

Revision as of 11:01, 7 May 2014

  • Full Real Name: Jaakko Matias Itkonen
  • Position: Student
  • Institution (NO ABBREVIATIONS): University of Helsinki, Faculty Of Pharmacy, Division of Pharmaceutical Biosciences
  • City, State/Province, Country: Helsinki, Finland
  • Field of Expertise or Study: Pharmacy

Introduction

Ciliary neutrophic factor (CNTF) is a nerve growth factor belonging to the IL-6 family of neuropoietic cytokines. Other members of this family include leukaemie inhibitory factor (LIF), IL-6, IL-11 and oncostatin M (Wang 2012). CNTF is a roughly 22 kDa protein consisting of a single peptide chain of 200 amino acid residues, and like many other cytokines, is folded into a four α-helix bundle.

Fig. 1 X-ray structure of a truncated form of hCNTF (2-187)


References

Proteopedia Page Contributors and Editors (what is this?)

Jaakko Itkonen, Eric Martz

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