4mhx

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'''Unreleased structure'''
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==Crystal Structure of Sulfamidase==
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<StructureSection load='4mhx' size='340' side='right' caption='[[4mhx]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4mhx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MHX OCA]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=FGP:2-AMINO-3-HYDROXY-3-PHOSPHONOOXY-PROPIONIC+ACID'>FGP</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4miv|4miv]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mhx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mhx RCSB], [http://www.ebi.ac.uk/pdbsum/4mhx PDBsum]</span></td></tr>
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<table>
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== Disease ==
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[[http://www.uniprot.org/uniprot/SPHM_HUMAN SPHM_HUMAN]] Sanfilippo syndrome type A. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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The entry 4mhx is ON HOLD until Paper Publication
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__TOC__
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</StructureSection>
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Authors: Sidhu, N.S., Uson, I., Schreiber, K., Proepper, K., Becker, S., Gaertner, J., Kraetzner, R., Steinfeld, R., Sheldrick, G.M.
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[[Category: N-sulfoglucosamine sulfohydrolase]]
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[[Category: Becker, S.]]
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Description: Crystal Structure of Sulfamidase
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[[Category: Gaertner, J.]]
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[[Category: Kraetzner, R.]]
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[[Category: Proepper, K.]]
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[[Category: Schreiber, K.]]
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[[Category: Sheldrick, G M.]]
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[[Category: Sidhu, N S.]]
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[[Category: Steinfeld, R.]]
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[[Category: Uson, I.]]
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[[Category: Heparan]]
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[[Category: Heparin]]
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[[Category: Hydrolase]]
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[[Category: Lysosome]]
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[[Category: Sulfatase fold]]

Revision as of 07:25, 14 May 2014

Crystal Structure of Sulfamidase

4mhx, resolution 2.00Å

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