3aqj

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[[Image:3aqj.png|left|200px]]
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==Crystal Structure of a C-terminal domain of the bacteriophage P2 tail spike protein, gpV==
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<StructureSection load='3aqj' size='340' side='right' caption='[[3aqj]], [[Resolution|resolution]] 1.27&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3aqj]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_p2 Enterobacteria phage p2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AQJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AQJ FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene><br>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">V ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10679 Enterobacteria phage P2])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3aqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aqj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3aqj RCSB], [http://www.ebi.ac.uk/pdbsum/3aqj PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The adsorption and infection of bacteriophage P2 is mediated by tail fibres and tail spikes. The tail spikes on the tail baseplate are used to irreversibly adsorb to the host cells. Recently, a P2 phage tail-spike protein, gpV, was purified and it was shown that a C-terminal domain, Ser87-Leu211, is sufficient for the binding of gpV to host Escherichia coli membranes [Kageyama et al. (2009), Biochemistry, 48, 10129-10135]. In this paper, the crystal structure of the C-terminal domain of P2 gpV is reported. The structure is a triangular pyramid and looks like a spearhead composed of an intertwined beta-sheet, a triple beta-helix and a metal-binding region containing iron, calcium and chloride ions.
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The host-binding domain of the P2 phage tail spike reveals a trimeric iron-binding structure.,Yamashita E, Nakagawa A, Takahashi J, Tsunoda K, Yamada S, Takeda S Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Aug 1;67(Pt 8):837-41., Epub 2011 Jul 13. PMID:21821878<ref>PMID:21821878</ref>
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The line below this paragraph, containing "STRUCTURE_3aqj", creates the "Structure Box" on the page.
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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or leave the SCENE parameter empty for the default display.
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{{STRUCTURE_3aqj| PDB=3aqj | SCENE= }}
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===Crystal Structure of a C-terminal domain of the bacteriophage P2 tail spike protein, gpV===
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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</div>
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_21821878}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 21821878 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_21821878}}
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==About this Structure==
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[[3aqj]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_p2 Enterobacteria phage p2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AQJ OCA].
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==Reference==
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<ref group="xtra">PMID:021821878</ref><references group="xtra"/>
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[[Category: Enterobacteria phage p2]]
[[Category: Enterobacteria phage p2]]
[[Category: Nakagawa, A.]]
[[Category: Nakagawa, A.]]

Revision as of 11:04, 14 May 2014

Crystal Structure of a C-terminal domain of the bacteriophage P2 tail spike protein, gpV

3aqj, resolution 1.27Å

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