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190d
From Proteopedia
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| - | [[Image:190d.gif|left|200px]] | + | [[Image:190d.gif|left|200px]] |
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| - | '''CRYSTAL STRUCTURE OF A FOUR-STRANDED INTERCALATED DNA: D(C4)''' | + | {{Structure |
| + | |PDB= 190d |SIZE=350|CAPTION= <scene name='initialview01'>190d</scene>, resolution 1.800Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
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| + | '''CRYSTAL STRUCTURE OF A FOUR-STRANDED INTERCALATED DNA: D(C4)''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 190D is a [ | + | 190D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=190D OCA]. |
==Reference== | ==Reference== | ||
| - | Crystal structure of a four-stranded intercalated DNA: d(C4)., Chen L, Cai L, Zhang X, Rich A, Biochemistry. 1994 Nov 22;33(46):13540-6. PMID:[http:// | + | Crystal structure of a four-stranded intercalated DNA: d(C4)., Chen L, Cai L, Zhang X, Rich A, Biochemistry. 1994 Nov 22;33(46):13540-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7947764 7947764] |
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Cai, L.]] | [[Category: Cai, L.]] | ||
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[[Category: u-dna]] | [[Category: u-dna]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 09:50:38 2008'' |
Revision as of 07:50, 20 March 2008
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| , resolution 1.800Å | |||||||
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| Coordinates: | save as pdb, mmCIF, xml | ||||||
CRYSTAL STRUCTURE OF A FOUR-STRANDED INTERCALATED DNA: D(C4)
Overview
The crystal structure of d(C4) solved at 2.3-A resolution reveals a four-stranded molecule composed of two interdigitated or intercalated duplexes. The duplexes are held together by hemiprotonated cytosine-cytosine base pairs and are parallel stranded, but the two duplexes point in opposite directions. The molecule has a slow right-handed twist of 12.4 degrees between covalently linked cytosine base pairs, and the base stacking distance is 3.1 A. This is in general agreement with the NMR studies. A biological role for DNA in this conformation is suggested.
About this Structure
190D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
Crystal structure of a four-stranded intercalated DNA: d(C4)., Chen L, Cai L, Zhang X, Rich A, Biochemistry. 1994 Nov 22;33(46):13540-6. PMID:7947764
Page seeded by OCA on Thu Mar 20 09:50:38 2008
