1a0t

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[[Image:1a0t.gif|left|200px]]<br /><applet load="1a0t" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1a0t.gif|left|200px]]
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caption="1a0t, resolution 2.4&Aring;" />
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'''SUCROSE-SPECIFIC PORIN, WITH BOUND SUCROSE MOLECULES'''<br />
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{{Structure
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|PDB= 1a0t |SIZE=350|CAPTION= <scene name='initialview01'>1a0t</scene>, resolution 2.4&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=SUC:SUCROSE'>SUC</scene> and <scene name='pdbligand=CA:CALCIUM ION'>CA</scene>
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|ACTIVITY=
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|GENE= SCRY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=602 Salmonella typhimurium])
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}}
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'''SUCROSE-SPECIFIC PORIN, WITH BOUND SUCROSE MOLECULES'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1A0T is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with <scene name='pdbligand=SUC:'>SUC</scene> and <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A0T OCA].
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1A0T is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A0T OCA].
==Reference==
==Reference==
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Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose., Forst D, Welte W, Wacker T, Diederichs K, Nat Struct Biol. 1998 Jan;5(1):37-46. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9437428 9437428]
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Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose., Forst D, Welte W, Wacker T, Diederichs K, Nat Struct Biol. 1998 Jan;5(1):37-46. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9437428 9437428]
[[Category: Salmonella typhimurium]]
[[Category: Salmonella typhimurium]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: porin]]
[[Category: porin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:39:36 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 09:51:16 2008''

Revision as of 07:51, 20 March 2008

Image:1a0t.gif


PDB ID 1a0t

Drag the structure with the mouse to rotate
, resolution 2.4Å
Ligands: and
Gene: SCRY (Salmonella typhimurium)
Coordinates: save as pdb, mmCIF, xml



SUCROSE-SPECIFIC PORIN, WITH BOUND SUCROSE MOLECULES


Overview

The X-ray structure of a sucrose-specific porin (ScrY) from Salmonella typhimurium has been determined by multiple isomorphous replacement at 2.4 A resolution both in its uncomplexed form and with bound sucrose. ScrY is a noncrystallographic trimer of identical subunits, each with 413 structurally well-defined amino acids. A monomer is built up of 18 anti-parallel beta-strands surrounding a hydrophilic pore, with a topology closely similar to that of maltoporin. Two non-overlapping sucrose-binding sites were identified in difference Fourier maps. The higher permeability for sucrose of ScrY as compared to maltoporin is mainly accounted for by differences in their pore-lining residues.

About this Structure

1A0T is a Single protein structure of sequence from Salmonella typhimurium. Full crystallographic information is available from OCA.

Reference

Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose., Forst D, Welte W, Wacker T, Diederichs K, Nat Struct Biol. 1998 Jan;5(1):37-46. PMID:9437428

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