4cj7
From Proteopedia
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| - | + | ==Structure of Crenactin, an archeal actin-like protein== | |
| - | + | <StructureSection load='4cj7' size='340' side='right' caption='[[4cj7]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[4cj7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrcj Pyrcj]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CJ7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CJ7 FirstGlance]. <br> | ||
| + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene><br> | ||
| + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cj7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cj7 RCSB], [http://www.ebi.ac.uk/pdbsum/4cj7 PDBsum]</span></td></tr> | ||
| + | <table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Polymerising proteins of the actin family are nearly ubiquitous. Crenactins, restricted to Crenarchaea, are more closely related to actin than bacterial MreB. Crenactins occur in gene clusters hinting at an unknown, but conserved function. We solved the crystal structure of crenactin at 3.2A resolution. The protein crystallises as a continuous right-handed helix with 8 subunits per complete turn, spanning 419A. The structure of crenactin shows several loops that are longer than in actin, but overall, crenactin is closely related to eukaryotic actin, with an RMSD of 1.6A. Crenactin filaments imaged by electron microscopy showed polymers with very similar helical parameters. | ||
| - | + | Crenactin from Pyrobaculum calidifontis is closely related to actin in structure and forms steep helical filaments.,Izore T, Duman R, Kureisaite-Ciziene D, Lowe J FEBS Lett. 2014 Jan 28. pii: S0014-5793(14)00058-1. doi:, 10.1016/j.febslet.2014.01.029. PMID:24486010<ref>PMID:24486010</ref> | |
| - | + | ||
| - | == | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
| - | + | </div> | |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Pyrcj]] | ||
[[Category: Duman, R E.]] | [[Category: Duman, R E.]] | ||
[[Category: Izore, T.]] | [[Category: Izore, T.]] | ||
Revision as of 13:24, 18 May 2014
Structure of Crenactin, an archeal actin-like protein
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Categories: Pyrcj | Duman, R E. | Izore, T. | Kureisaite-Ciziene, D. | Lowe, J. | Archea | Filament | Parm | Structural protein
