1a7h

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[[Image:1a7h.gif|left|200px]]<br /><applet load="1a7h" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1a7h.gif|left|200px]]
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caption="1a7h, resolution 2.56&Aring;" />
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'''GAMMA S CRYSTALLIN C-TERMINAL DOMAIN'''<br />
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{{Structure
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|PDB= 1a7h |SIZE=350|CAPTION= <scene name='initialview01'>1a7h</scene>, resolution 2.56&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE= CRYGS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 Bos taurus])
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}}
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'''GAMMA S CRYSTALLIN C-TERMINAL DOMAIN'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1A7H is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A7H OCA].
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1A7H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A7H OCA].
==Reference==
==Reference==
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The C-terminal domains of gammaS-crystallin pair about a distorted twofold axis., Basak AK, Kroone RC, Lubsen NH, Naylor CE, Jaenicke R, Slingsby C, Protein Eng. 1998 May;11(5):337-44. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9681865 9681865]
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The C-terminal domains of gammaS-crystallin pair about a distorted twofold axis., Basak AK, Kroone RC, Lubsen NH, Naylor CE, Jaenicke R, Slingsby C, Protein Eng. 1998 May;11(5):337-44. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9681865 9681865]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: multigene family]]
[[Category: multigene family]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:41:42 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 09:54:00 2008''

Revision as of 07:54, 20 March 2008

Image:1a7h.gif


PDB ID 1a7h

Drag the structure with the mouse to rotate
, resolution 2.56Å
Gene: CRYGS (Bos taurus)
Coordinates: save as pdb, mmCIF, xml



GAMMA S CRYSTALLIN C-TERMINAL DOMAIN


Overview

The 2-domain gammaS-crystallin, a highly conserved early evolutionary off-shoot of the gamma-crystallin family, is located in the water-rich region of eye lenses. The expressed C-terminal domain, gammaS-C, has been crystallized and the 2.56 A X-ray structure determined. There are two domains in the asymmetric unit which pair about a distorted twofold axis. One of the domains has an altered conformation in a highly conserved region of the protein, the tyrosine corner. The distorted gammaS-C dimer of domains is compared with the highly symmetrical, equivalent recombinant dimer of C-terminal domains from gammaB-crystallin. Sequence changes close to the interface, that distinguish gammaS from the other gamma-crystallins, are examined in order to evaluate their role in symmetrical domain pairing.

About this Structure

1A7H is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

The C-terminal domains of gammaS-crystallin pair about a distorted twofold axis., Basak AK, Kroone RC, Lubsen NH, Naylor CE, Jaenicke R, Slingsby C, Protein Eng. 1998 May;11(5):337-44. PMID:9681865

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