1a7s

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[[Image:1a7s.gif|left|200px]]<br /><applet load="1a7s" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1a7s.gif|left|200px]]
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caption="1a7s, resolution 1.12&Aring;" />
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'''ATOMIC RESOLUTION STRUCTURE OF HBP'''<br />
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{{Structure
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|PDB= 1a7s |SIZE=350|CAPTION= <scene name='initialview01'>1a7s</scene>, resolution 1.12&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=EOH:ETHANOL'>EOH</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''ATOMIC RESOLUTION STRUCTURE OF HBP'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1A7S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=EOH:'>EOH</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A7S OCA].
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1A7S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A7S OCA].
==Reference==
==Reference==
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Atomic resolution structure of human HBP/CAP37/azurocidin., Karlsen S, Iversen LF, Larsen IK, Flodgaard HJ, Kastrup JS, Acta Crystallogr D Biol Crystallogr. 1998 Jul 1;54(Pt 4):598-609. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9761855 9761855]
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Atomic resolution structure of human HBP/CAP37/azurocidin., Karlsen S, Iversen LF, Larsen IK, Flodgaard HJ, Kastrup JS, Acta Crystallogr D Biol Crystallogr. 1998 Jul 1;54(Pt 4):598-609. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9761855 9761855]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: serine protease homolog]]
[[Category: serine protease homolog]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:41:49 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 09:54:08 2008''

Revision as of 07:54, 20 March 2008

Image:1a7s.gif


PDB ID 1a7s

Drag the structure with the mouse to rotate
, resolution 1.12Å
Ligands: , and
Coordinates: save as pdb, mmCIF, xml



ATOMIC RESOLUTION STRUCTURE OF HBP


Overview

Crystals of human heparin binding protein (HBP) diffract to 1.1 A when flash-frozen at 120 K. The atomic resolution structure has been refined anisotropically using SHELXL96. The final model of HBP consists of 221 amino-acid residues of 225 possible, three glycosylation units, one chloride ion, 15 precipitant ethanol molecules and 323 water molecules. The structure is refined to a final crystallographic R factor of 15.9% and Rfree(5%) of 18.9% using all data. A putative protein kinase C activation site has been identified, involving residues 113-120. The structure is compared to the previously determined 2.3 A resolution structure of HBP.

About this Structure

1A7S is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Atomic resolution structure of human HBP/CAP37/azurocidin., Karlsen S, Iversen LF, Larsen IK, Flodgaard HJ, Kastrup JS, Acta Crystallogr D Biol Crystallogr. 1998 Jul 1;54(Pt 4):598-609. PMID:9761855

Page seeded by OCA on Thu Mar 20 09:54:08 2008

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