3waf
From Proteopedia
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| - | ''' | + | ==X-ray structure of apo-TtFbpA, a ferric ion-binding protein from thermus thermophilus HB8== |
| + | <StructureSection load='3waf' size='340' side='right' caption='[[3waf]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3waf]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WAF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WAF FirstGlance]. <br> | ||
| + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene><br> | ||
| + | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wae|3wae]]</td></tr> | ||
| + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3waf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3waf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3waf RCSB], [http://www.ebi.ac.uk/pdbsum/3waf PDBsum]</span></td></tr> | ||
| + | <table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Crystal structures of FbpA, the periplasmic ferric ion-binding protein of an iron-uptake ABC transporter, from Thermus thermophilus HB8 (TtFbpA) have been solved in apo and ferric ion-bound forms at 1.8 and 1.7 A resolution, respectively. The latter crystal structure shows that the bound ferric ion forms a novel six-coordinated complex with three tyrosine side chains, two bicarbonates and a water molecule in the metal-binding site. The results of gel-filtration chromatography and dynamic light scattering show that TtFbpA exists as a monomer in solution regardless of ferric ion binding and that TtFbpA adopts a more compact conformation in the ferric ion-bound state than in the apo state in solution. | ||
| - | + | A novel mode of ferric ion coordination by the periplasmic ferric ion-binding subunit FbpA of an ABC-type iron transporter from Thermus thermophilus HB8.,Wang S, Ogata M, Horita S, Ohtsuka J, Nagata K, Tanokura M Acta Crystallogr D Biol Crystallogr. 2014 Jan;70(Pt 1):196-202. doi:, 10.1107/S1399004713026333. Epub 2013 Dec 31. PMID:24419392<ref>PMID:24419392</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Horita, S.]] | ||
| + | [[Category: Nagata, K.]] | ||
| + | [[Category: Ogata, M.]] | ||
| + | [[Category: Ohtsuka, J.]] | ||
| + | [[Category: Tanokura, M.]] | ||
| + | [[Category: Wang, S.]] | ||
| + | [[Category: Abc transporter]] | ||
| + | [[Category: Metal binding protein]] | ||
| + | [[Category: Peamease]] | ||
| + | [[Category: Periplasmic binding protein]] | ||
| + | [[Category: Ttha1628]] | ||
Revision as of 09:07, 21 May 2014
X-ray structure of apo-TtFbpA, a ferric ion-binding protein from thermus thermophilus HB8
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