4lte

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'''Unreleased structure'''
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==Structure of Cysteine-free Human Insulin Degrading Enzyme in Complex with Macrocyclic Inhibitor==
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<StructureSection load='4lte' size='340' side='right' caption='[[4lte]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
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The entry 4lte is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4lte]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LTE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LTE FirstGlance]. <br>
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Authors: Foda, Z.H., Seeliger, M.A., Saghatelian, A., Liu, D.R.
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DFF:4-BENZOYL-D-PHENYLALANINE'>DFF</scene>, <scene name='pdbligand=FUM:FUMARIC+ACID'>FUM</scene>, <scene name='pdbligand=LYN:2,6-DIAMINO-HEXANOIC+ACID+AMIDE'>LYN</scene></td></tr>
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Description: Structure of Cysteine-free Human Insulin Degrading Enzyme in Complex with Macrocyclic Inhibitor
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Insulysin Insulysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.56 3.4.24.56] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lte FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lte OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lte RCSB], [http://www.ebi.ac.uk/pdbsum/4lte PDBsum]</span></td></tr>
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<table>
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__TOC__
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</StructureSection>
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[[Category: Insulysin]]
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[[Category: Foda, Z H.]]
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[[Category: Liu, D R.]]
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[[Category: Saghatelian, A.]]
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[[Category: Seeliger, M A.]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Metal-binding]]
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[[Category: Metalloprotease]]
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[[Category: Protease]]

Revision as of 09:21, 21 May 2014

Structure of Cysteine-free Human Insulin Degrading Enzyme in Complex with Macrocyclic Inhibitor

4lte, resolution 2.71Å

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