4o6e
From Proteopedia
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| - | ''' | + | ==Discovery of 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine Inhibitors of Erk2== |
| - | + | <StructureSection load='4o6e' size='340' side='right' caption='[[4o6e]], [[Resolution|resolution]] 1.95Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4o6e]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O6E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O6E FirstGlance]. <br> | |
| - | + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2SH:N-[(1S)-1-(3-CHLORO-4-FLUOROPHENYL)-2-HYDROXYETHYL]-2-(TETRAHYDRO-2H-PYRAN-4-YLAMINO)-5,8-DIHYDROPYRIDO[3,4-D]PYRIMIDINE-7(6H)-CARBOXAMIDE'>2SH</scene><br> | |
| - | + | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24] </span></td></tr> | |
| - | + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o6e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o6e RCSB], [http://www.ebi.ac.uk/pdbsum/4o6e PDBsum]</span></td></tr> | |
| + | <table> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Mitogen-activated protein kinase]] | ||
| + | [[Category: Wang, W.]] | ||
| + | [[Category: Yin, J.]] | ||
| + | [[Category: Protein kinase]] | ||
| + | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 09:24, 21 May 2014
Discovery of 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine Inhibitors of Erk2
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