We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

Tubulin

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 33: Line 33:
[[2bto]] – PdTUBA+thioredoxin 1 – ''Prosthecobacter dejongeii''<br />
[[2bto]] – PdTUBA+thioredoxin 1 – ''Prosthecobacter dejongeii''<br />
 +
[[2e4h]] – hTUBA C terminal + restin CAP-Gly domain 2 – human<br />
===α-tubulin + β-tubulin===
===α-tubulin + β-tubulin===
Line 39: Line 40:
[[4f61]] - sTUBA+sTUBB+stathmin-like protein R4<br />
[[4f61]] - sTUBA+sTUBB+stathmin-like protein R4<br />
[[3ut5]] - sTUBA+sTUBB+stathmin-like protein B3 + vinca peptide<br />
[[3ut5]] - sTUBA+sTUBB+stathmin-like protein B3 + vinca peptide<br />
 +
[[4eb6]] - sTUBA+sTUBB+stathmin-4<br />
[[4drx]] - sTUBA+sTUBB + ankyrin repeat protein<br />
[[4drx]] - sTUBA+sTUBB + ankyrin repeat protein<br />
[[4f6r]] - sTUBA+sTUBB+stathmin-like protein R1 + ankyrin repeat protein<br />
[[4f6r]] - sTUBA+sTUBB+stathmin-like protein R1 + ankyrin repeat protein<br />
[[2wbe]] – bTUBA1D+bTUBB2B+kinesin+AMPPNP – bovine<br />
[[2wbe]] – bTUBA1D+bTUBB2B+kinesin+AMPPNP – bovine<br />
[[3dco]] - bTUBA+bTUBB+kinesin-like NOD<br />
[[3dco]] - bTUBA+bTUBB+kinesin-like NOD<br />
 +
[[4ck5]], [[4kc6]], [[4kc7]] - bTUBA+bTUBB+kinesin-like KIF11 motor domain<br />
[[1tvk]] - bTUBA+bTUBB+GDP+GTP+Epothilone A – electron crystallography<br />
[[1tvk]] - bTUBA+bTUBB+GDP+GTP+Epothilone A – electron crystallography<br />
[[3iz0]] - bTUBA+bTUBB+hNDC80/SPC25+hNUF2/SPC24 – electron microscopy<br />
[[3iz0]] - bTUBA+bTUBB+hNDC80/SPC25+hNUF2/SPC24 – electron microscopy<br />
Line 49: Line 52:
[[3du7]], [[3e22]], [[1z2b]], [[1sa0]], [[1sa1]] – bTUBA1C+bTUBB2B+stathmin-like protein B3<br />
[[3du7]], [[3e22]], [[1z2b]], [[1sa0]], [[1sa1]] – bTUBA1C+bTUBB2B+stathmin-like protein B3<br />
[[1ffx]] - bTUBA+bTUBB+stathmin-like protein B3<br />
[[1ffx]] - bTUBA+bTUBB+stathmin-like protein B3<br />
 +
[[4o2a]] - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase<br />
 +
[[4o2b]] - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase + colchicine<br />
 +
[[4o4h]] - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase + laulimalide<br />
 +
[[4o4i]] - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase + epothilone + laulimalide<br />
 +
[[4o4j]] - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase + peloruside<br />
 +
[[4o4l]] - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase + peloruside + epothilone<br />
[[1jff]] - bTUBA+bTUBB<br />
[[1jff]] - bTUBA+bTUBB<br />
[[4hna]] - bTUBA+bTUBB + kinesin heavy chain + ankyrin repeat protein<br />
[[4hna]] - bTUBA+bTUBB + kinesin heavy chain + ankyrin repeat protein<br />
Line 77: Line 86:
=== FtsZ ===
=== FtsZ ===
-
[[2rhh]], [[2rhj]] – BsFtsZ+SO4 – ''Bacillus subtilis''<br />
+
[[2vxy]], [[2vam]] – BsFtsZ - ''Bacillus subtilis''<br />
 +
[[2ve8]] – PaFtsZ gamma domain – ''Pseudomonas aeruginosa''<br />
 +
[[2r6r]]– AaFtsZ - ''Aquifex aeolicus''<br />
 +
[[1w59]], [[1fsz]] – MjFtsZ - ''Methancaldococcus jannaschii''<br />
 +
[[1w5e]], [[1w5f]] – MjFtsZ (mutant) <br />
 +
[[3v3t]] – FtsZ (mutant) – ''Clostridium botulinum''<br />
 +
[[3zid]] – FtsZ – ''Methanosaeta thermophila''<br />
 +
[[3vo9]], [[3vpa]] - SaFtsZ – ''Staphylococcus aureus''<br />
 +
[[3wgj]], [[3wgk]] – SaFtsZ (mutant) <br />
 +
 
 +
===FtsZ complexes===
 +
 
 +
[[2rhh]], [[2rhj]] – BsFtsZ+SO4 <br />
[[2rhl]] - BsFtsZ+GDP<br />
[[2rhl]] - BsFtsZ+GDP<br />
[[2rho]] - BsFtsZ+GDP+GTP-gamma-S<br />
[[2rho]] - BsFtsZ+GDP+GTP-gamma-S<br />
-
[[2vxy]], [[2vam]] – BsFtsZ<br />
 
-
[[2ve8]] – PaFtsZ gamma domain – ''Pseudomonas aeruginosa''<br />
 
[[2ve9]] - PaFtsZ gamma domain+DNA<br />
[[2ve9]] - PaFtsZ gamma domain+DNA<br />
[[2vaw]] – PaFtsZ+GDP<br />
[[2vaw]] – PaFtsZ+GDP<br />
[[1ofu]] - PaFtsZ+SULA<br />
[[1ofu]] - PaFtsZ+SULA<br />
-
[[2r75]] - AaFtsZ+8-morpholino-GTP – ''Aquifex aeolicus''<br />
+
[[2r75]] - AaFtsZ+8-morpholino-GTP <br />
-
[[2r6r]] - AaFtsZ<br />
+
[[2q1x]], [[1rq2]] - MtFtsZ+citrate – ''Mycobacterium tuberculosis''<br />
[[2q1x]], [[1rq2]] - MtFtsZ+citrate – ''Mycobacterium tuberculosis''<br />
[[2q1y]], [[1rlu]] - MtFtsZ+GTP-gamma-S<br />
[[2q1y]], [[1rlu]] - MtFtsZ+GTP-gamma-S<br />
-
[[1rq7]] - MtFtsZ+GDP<br />
+
[[1rq7]], [[4kwe]] - MtFtsZ+GDP<br />
-
[[2vap]] – MjFtsZ+GDP – ''Methancaldococcus jannaschii''<br />
+
[[2vap]] – MjFtsZ+GDP <br />
[[1w58]] - MjFtsZ+GMPCPP<br />
[[1w58]] - MjFtsZ+GMPCPP<br />
-
[[1w59]], [[1fsz]] – MjFtsZ<br />
 
[[1w5a]] - MjFtsZ+MgGTP<br />
[[1w5a]] - MjFtsZ+MgGTP<br />
[[1w5b]] - MjFtsZ+GTP<br />
[[1w5b]] - MjFtsZ+GTP<br />
-
[[1w5e]], [[1w5f]] – MjFtsZ (mutant)
+
[[4b45]] – HvFtsZ + GTP-γS – ''Haloferax volcanii''<br />
 +
[[3vo8]], [[3voa]] - SaFtsZ + GDP <br />
 +
[[3wgl]] – SaFtsZ (mutant) + GDP<br />
 +
[[3wgn]] – SaFtsZ + GTP-γS<br />
 +
[[3wgm]] – SaFtsZ (mutant) + GTP<br />
 +
[[3vob]] - SaFtsZ + GDP + benzamide derivative<br />
 +
[[4dxd]] - SaFtsZ + antibiotic <br />
 +
[[4b46]] - HvFtsZ + GDP <br />
 +
[[4m8i]] - SeFtsZ + GDP – ''Staphylococcus epidermitis''<br />
 +
 
 +
 
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:57, 26 May 2014

Image:1z5w.png
Crystal Structure of Tubulin 1z5w

Template:STRUCTURE 1z5w










Tubulin (TUB) is a constituent of microtubules in eukaryotes. Microtubules are assembled from dimers of α-tubulin (TUBA) and β-tubulin (TUBB) bound to GTP. γ-tubulin (TUBG) is part of the nucleation of microtubules. Human TUB contains several numbered subtypes. FtsZ (Filamenting temperature-sensitive mutant Z) is a prokaryotic homologue of TUB. The images at the left and at the right correspond to one representative Tubulin, i.e. the crystal structure of Tubulin (1z5w).

Contents

3D Structures of Tubulin

Updated on 26-May-2014

Tubulin

α-tubulin

2bto – PdTUBA+thioredoxin 1 – Prosthecobacter dejongeii
2e4h – hTUBA C terminal + restin CAP-Gly domain 2 – human

α-tubulin + β-tubulin

3hkb, 3hkc, 3hkd, 3hke, 3n2g, 3n2k, 3ryc, 3ryf, 3ryh, 3ryi – sTUBA+sTUBB+stathmin-like protein B3 – sheep
4f61 - sTUBA+sTUBB+stathmin-like protein R4
3ut5 - sTUBA+sTUBB+stathmin-like protein B3 + vinca peptide
4eb6 - sTUBA+sTUBB+stathmin-4
4drx - sTUBA+sTUBB + ankyrin repeat protein
4f6r - sTUBA+sTUBB+stathmin-like protein R1 + ankyrin repeat protein
2wbe – bTUBA1D+bTUBB2B+kinesin+AMPPNP – bovine
3dco - bTUBA+bTUBB+kinesin-like NOD
4ck5, 4kc6, 4kc7 - bTUBA+bTUBB+kinesin-like KIF11 motor domain
1tvk - bTUBA+bTUBB+GDP+GTP+Epothilone A – electron crystallography
3iz0 - bTUBA+bTUBB+hNDC80/SPC25+hNUF2/SPC24 – electron microscopy
3edl - bTUBA1D+bTUBB2B+kinesin motor domain
2xrp - bTUBA1D+bTUBB2B+doublecortin
3du7, 3e22, 1z2b, 1sa0, 1sa1 – bTUBA1C+bTUBB2B+stathmin-like protein B3
1ffx - bTUBA+bTUBB+stathmin-like protein B3
4o2a - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase
4o2b - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase + colchicine
4o4h - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase + laulimalide
4o4i - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase + epothilone + laulimalide
4o4j - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase + peloruside
4o4l - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase + peloruside + epothilone
1jff - bTUBA+bTUBB
4hna - bTUBA+bTUBB + kinesin heavy chain + ankyrin repeat protein
4ihj - bTUBA+bTUBB+stathmin-like protein B3 + tubulin tyrosine ligase + ADP
4iij, 4i55 - bTUBA+bTUBB+stathmin-like protein B3 + tubulin tyrosine ligase
3j1t, 3j1u - bTUBA+bTUBB+ dyenin
3j2u - bTUBA+bTUBB+kinesin-like KLP10A head domain
4i50, 4i4t - bTUBA+bTUBB+stathmin-like protein B3 + tubulin tyrosine ligase + anti-cancer agent
2p4n - hTUBA+hTUBB+kinesin heavy chain
2hxf - pTUBA+pTUBB+kinesin-like KIF1A+AMPPNP – pig
2hxh - pTUBA+pTUBB+kinesin-like KIF1A+ADP
1ia0 - pTUBA+pTUBB+kinesin-like KIF1A+ATP
4abo - pTUBA+pTUBB+ microtubule integrity protein MAL3
1tub - pTUBA+pTUBB – electron diffraction
4aqv, 4aqw - bTUBA+bTUBB+kinesin-like KIF11 – Cryo EM
4atu - bTUBA1D+bTUBB2B+doublecortin – Cryo EM
4atx - bTUBA1D+bTUBB2B+kinesin motor domain – Cryo EM
2btq – PdTUBA+PdTUBB
4ffb - TUBA+TUBB (mutant) + protein STU2 - yeast

γ-tubulin

3cb2 – hTUBG1+GDP
1z5v - hTUBG1+GTPgS
1z5w - hTUBG1+GTP
3rip – hTUBG4

FtsZ

2vxy, 2vam – BsFtsZ - Bacillus subtilis
2ve8 – PaFtsZ gamma domain – Pseudomonas aeruginosa
2r6r– AaFtsZ - Aquifex aeolicus
1w59, 1fsz – MjFtsZ - Methancaldococcus jannaschii
1w5e, 1w5f – MjFtsZ (mutant)
3v3t – FtsZ (mutant) – Clostridium botulinum
3zid – FtsZ – Methanosaeta thermophila
3vo9, 3vpa - SaFtsZ – Staphylococcus aureus
3wgj, 3wgk – SaFtsZ (mutant)

FtsZ complexes

2rhh, 2rhj – BsFtsZ+SO4
2rhl - BsFtsZ+GDP
2rho - BsFtsZ+GDP+GTP-gamma-S
2ve9 - PaFtsZ gamma domain+DNA
2vaw – PaFtsZ+GDP
1ofu - PaFtsZ+SULA
2r75 - AaFtsZ+8-morpholino-GTP
2q1x, 1rq2 - MtFtsZ+citrate – Mycobacterium tuberculosis
2q1y, 1rlu - MtFtsZ+GTP-gamma-S
1rq7, 4kwe - MtFtsZ+GDP
2vap – MjFtsZ+GDP
1w58 - MjFtsZ+GMPCPP
1w5a - MjFtsZ+MgGTP
1w5b - MjFtsZ+GTP
4b45 – HvFtsZ + GTP-γS – Haloferax volcanii
3vo8, 3voa - SaFtsZ + GDP
3wgl – SaFtsZ (mutant) + GDP
3wgn – SaFtsZ + GTP-γS
3wgm – SaFtsZ (mutant) + GTP
3vob - SaFtsZ + GDP + benzamide derivative
4dxd - SaFtsZ + antibiotic
4b46 - HvFtsZ + GDP
4m8i - SeFtsZ + GDP – Staphylococcus epidermitis

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/Tubulin"
Personal tools