1aft
From Proteopedia
(Difference between revisions)
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| - | [[Image:1aft.gif|left|200px]] | + | [[Image:1aft.gif|left|200px]] |
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| - | '''SMALL SUBUNIT C-TERMINAL INHIBITORY PEPTIDE OF MOUSE RIBONUCLEOTIDE REDUCTASE AS BOUND TO THE LARGE SUBUNIT, NMR, 26 STRUCTURES''' | + | {{Structure |
| + | |PDB= 1aft |SIZE=350|CAPTION= <scene name='initialview01'>1aft</scene> | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=ACE:ACETYL GROUP'>ACE</scene> | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''SMALL SUBUNIT C-TERMINAL INHIBITORY PEPTIDE OF MOUSE RIBONUCLEOTIDE REDUCTASE AS BOUND TO THE LARGE SUBUNIT, NMR, 26 STRUCTURES''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1AFT is a [ | + | 1AFT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AFT OCA]. |
==Reference== | ==Reference== | ||
| - | NMR structure of an inhibitory R2 C-terminal peptide bound to mouse ribonucleotide reductase R1 subunit., Fisher A, Laub PB, Cooperman BS, Nat Struct Biol. 1995 Nov;2(11):951-5. PMID:[http:// | + | NMR structure of an inhibitory R2 C-terminal peptide bound to mouse ribonucleotide reductase R1 subunit., Fisher A, Laub PB, Cooperman BS, Nat Struct Biol. 1995 Nov;2(11):951-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7583667 7583667] |
[[Category: Ribonucleoside-diphosphate reductase]] | [[Category: Ribonucleoside-diphosphate reductase]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: ACE]] | [[Category: ACE]] | ||
[[Category: nonstandard type i turn]] | [[Category: nonstandard type i turn]] | ||
| - | [[Category: peptide | + | [[Category: peptide inhibitor]] |
| - | [[Category: restrained molecular | + | [[Category: restrained molecular dynamic]] |
[[Category: ribonucleotide reductase]] | [[Category: ribonucleotide reductase]] | ||
[[Category: transferred noesy]] | [[Category: transferred noesy]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 09:56:56 2008'' |
Revision as of 07:56, 20 March 2008
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| Ligands: | |||||||
| Activity: | Ribonucleoside-diphosphate reductase, with EC number 1.17.4.1 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
SMALL SUBUNIT C-TERMINAL INHIBITORY PEPTIDE OF MOUSE RIBONUCLEOTIDE REDUCTASE AS BOUND TO THE LARGE SUBUNIT, NMR, 26 STRUCTURES
Overview
The structure of peptide N-AcYTLDADF when bound to the large subunit of mouse ribonucleotide reductase has been elucidated by transfer NOE. This structure suggests a general design for type 1 RR inhibitors.
About this Structure
1AFT is a Single protein structure of sequence from [1]. Full crystallographic information is available from OCA.
Reference
NMR structure of an inhibitory R2 C-terminal peptide bound to mouse ribonucleotide reductase R1 subunit., Fisher A, Laub PB, Cooperman BS, Nat Struct Biol. 1995 Nov;2(11):951-5. PMID:7583667
Page seeded by OCA on Thu Mar 20 09:56:56 2008
