4qag
From Proteopedia
(Difference between revisions)
m (Protected "4qag" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | ''' | + | ==Structure of a dihydroxycoumarin active-site inhibitor in complex with the RNASE H domain of HIV-1 reverse transcriptase== |
| - | + | <StructureSection load='4qag' size='340' side='right' caption='[[4qag]], [[Resolution|resolution]] 1.71Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4qag]] is a 2 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4je2 4je2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QAG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QAG FirstGlance]. <br> | |
| - | + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F95:(7,8-DIHYDROXY-2-OXO-2H-CHROMEN-4-YL)ACETIC+ACID'>F95</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene><br> | |
| - | + | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3k2p|3k2p]], [[3ig1|3ig1]], [[3qlh|3qlh]], [[3ifj|3ifj]], [[4g1q|4g1q]]</td></tr> | |
| - | + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qag OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qag RCSB], [http://www.ebi.ac.uk/pdbsum/4qag PDBsum]</span></td></tr> | |
| + | <table> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arnold, E.]] | ||
| + | [[Category: Himmel, D M.]] | ||
| + | [[Category: Ho, W C.]] | ||
| + | [[Category: Active site]] | ||
| + | [[Category: Aid]] | ||
| + | [[Category: Dihydroxy-benzopyrone derivative]] | ||
| + | [[Category: Dihydroxycoumarin analog]] | ||
| + | [[Category: Divalent cation chelator]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
| + | [[Category: Protein-inhibitor complex]] | ||
| + | [[Category: Reverse transcriptase]] | ||
| + | [[Category: Rnase h inhibitor]] | ||
| + | [[Category: Structure-based drug design]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 05:04, 4 June 2014
Structure of a dihydroxycoumarin active-site inhibitor in complex with the RNASE H domain of HIV-1 reverse transcriptase
| |||||||||||
Categories: Arnold, E. | Himmel, D M. | Ho, W C. | Active site | Aid | Dihydroxy-benzopyrone derivative | Dihydroxycoumarin analog | Divalent cation chelator | Hydrolase-hydrolase inhibitor complex | Protein-inhibitor complex | Reverse transcriptase | Rnase h inhibitor | Structure-based drug design | Transferase
