4kzs
From Proteopedia
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| - | ''' | + | ==Crystal structure of the secreted protein HP1454 from the human pathogen Helicobacter pylori== |
| + | <StructureSection load='4kzs' size='340' side='right' caption='[[4kzs]], [[Resolution|resolution]] 2.70Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4kzs]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KZS FirstGlance]. <br> | ||
| + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene><br> | ||
| + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kzs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kzs RCSB], [http://www.ebi.ac.uk/pdbsum/4kzs PDBsum]</span></td></tr> | ||
| + | <table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | HP1454 is a protein of 303 amino acids found in the extracellular milieu of Helicobacter pylori. The protein structure, crystallized in the orthorhombic C2221 space group with one molecule per asymmetric unit, has been determined using the SAD method. HP1454 exhibits an elongated bent shape, composed of three distinct domains. Each domain possesses a fold already present in other structures: domain I contains a three-strand antiparallel beta-barrel flanked by a long alpha-helix, domain II is an anti-parallel three-helix bundle, and domain III a beta-sheet flanked by two alpha-helices. The overall assembly of the protein does not bear any similarity with known structures. (c) Proteins 2014;. (c) 2014 Wiley Periodicals, Inc. | ||
| - | + | Crystal structure of the secreted protein HP1454 from the human pathogen Helicobacter pylori.,Quarantini S, Cendron L, Zanotti G Proteins. 2014 May 23. doi: 10.1002/prot.24608. PMID:24854568<ref>PMID:24854568</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Cendron, L.]] | ||
| + | [[Category: Fischer, W.]] | ||
| + | [[Category: Quarantini, S.]] | ||
| + | [[Category: Zanotti, G.]] | ||
| + | [[Category: Helicobacter pylori]] | ||
| + | [[Category: Outer membrane]] | ||
| + | [[Category: Secreted protein]] | ||
| + | [[Category: Three-helix bundle]] | ||
| + | [[Category: Tol-pal system]] | ||
| + | [[Category: Unknown function]] | ||
Revision as of 05:05, 4 June 2014
Crystal structure of the secreted protein HP1454 from the human pathogen Helicobacter pylori
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