3srk
From Proteopedia
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| - | [[ | + | ==A new class of suicide inhibitor blocks nucleotide binding to pyruvate kinase== |
| + | <StructureSection load='3srk' size='340' side='right' caption='[[3srk]], [[Resolution|resolution]] 2.65Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3srk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SRK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SRK FirstGlance]. <br> | ||
| + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=LSA:1,2-BENZISOTHIAZOL-3(2H)-ONE+1,1-DIOXIDE'>LSA</scene>, <scene name='pdbligand=PTK:PYRENE-1,3,6,8-TETRASULFONIC+ACID'>PTK</scene><br> | ||
| + | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1pkl|1pkl]]</td></tr> | ||
| + | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PYK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5665 Leishmania mexicana])</td></tr> | ||
| + | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_kinase Pyruvate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.40 2.7.1.40] </span></td></tr> | ||
| + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3srk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3srk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3srk RCSB], [http://www.ebi.ac.uk/pdbsum/3srk PDBsum]</span></td></tr> | ||
| + | <table> | ||
| - | + | ==See Also== | |
| - | + | *[[Pyruvate Kinase|Pyruvate Kinase]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | + | ||
| - | [[ | + | |
[[Category: Leishmania mexicana]] | [[Category: Leishmania mexicana]] | ||
[[Category: Pyruvate kinase]] | [[Category: Pyruvate kinase]] | ||
Revision as of 05:24, 5 June 2014
A new class of suicide inhibitor blocks nucleotide binding to pyruvate kinase
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Categories: Leishmania mexicana | Pyruvate kinase | Auld, D S. | Blackburn, E A. | Boxer, M. | Fothergill-Gilmore, L A. | McNae, I W. | Michels, P A.M. | Morgan, H P. | Shen, M. | Walkinshaw, M D. | Walsh, M. | Wear, M A. | Phosphenolpyruvate | Phospho transfer | Sugar kinase | Tim barrel | Transferase-inhibitor complex
