3sub

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[[Image:3sub.png|left|200px]]
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==Crystal structure of the catalytic domain of Plasmodium falciparum ARF GTPase activating protein==
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<StructureSection load='3sub' size='340' side='right' caption='[[3sub]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3sub]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum_3d7 Plasmodium falciparum 3d7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SUB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SUB FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PFL2140c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 Plasmodium falciparum 3D7])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sub OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sub RCSB], [http://www.ebi.ac.uk/pdbsum/3sub PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The crystal structure of the catalytic domain of the ADP ribosylation factor GTPase-activating protein (ARFGAP) from Plasmodium falciparum has been determined and refined to 2.4 A resolution. Multiwavength anomalous diffraction (MAD) data were collected utilizing the Zn(2+) ion bound at the zinc-finger domain and were used to solve the structure. The overall structure of the domain is similar to those of mammalian ARFGAPs. However, several amino-acid residues in the area where GAP interacts with ARF1 differ in P. falciparum ARFGAP. Moreover, a number of residues that form the dimer interface in the crystal structure are unique in P. falciparum ARFGAP.
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Structure of the catalytic domain of Plasmodium falciparum ARF GTPase-activating protein (ARFGAP).,Cook WJ, Senkovich O, Chattopadhyay D Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Nov 1;67(Pt 11):1339-44., Epub 2011 Oct 25. PMID:22102228<ref>PMID:22102228</ref>
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The line below this paragraph, containing "STRUCTURE_3sub", creates the "Structure Box" on the page.
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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or leave the SCENE parameter empty for the default display.
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{{STRUCTURE_3sub| PDB=3sub | SCENE= }}
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===Crystal structure of the catalytic domain of Plasmodium falciparum ARF GTPase activating protein===
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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</div>
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_22102228}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 22102228 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_22102228}}
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==About this Structure==
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[[3sub]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum_3d7 Plasmodium falciparum 3d7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SUB OCA].
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==Reference==
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<ref group="xtra">PMID:022102228</ref><references group="xtra"/>
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[[Category: Plasmodium falciparum 3d7]]
[[Category: Plasmodium falciparum 3d7]]
[[Category: Chattopadhyay, D.]]
[[Category: Chattopadhyay, D.]]

Revision as of 05:24, 5 June 2014

Crystal structure of the catalytic domain of Plasmodium falciparum ARF GTPase activating protein

3sub, resolution 2.40Å

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