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3sqf

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[[Image:3sqf.png|left|200px]]
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==Crystal structure of monomeric M-PMV retroviral protease==
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<StructureSection load='3sqf' size='340' side='right' caption='[[3sqf]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3sqf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SQF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SQF FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nso|1nso]], [[3hvp|3hvp]], [[4hvp|4hvp]], [[2rsp|2rsp]], [[1yth|1yth]], [[4fiv|4fiv]], [[2fmb|2fmb]], [[3liy|3liy]], [[3nr6|3nr6]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pro, prt ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11855 MPMV])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sqf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sqf RCSB], [http://www.ebi.ac.uk/pdbsum/3sqf PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Following the failure of a wide range of attempts to solve the crystal structure of M-PMV retroviral protease by molecular replacement, we challenged players of the protein folding game Foldit to produce accurate models of the protein. Remarkably, Foldit players were able to generate models of sufficient quality for successful molecular replacement and subsequent structure determination. The refined structure provides new insights for the design of antiretroviral drugs.
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<!--
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Crystal structure of a monomeric retroviral protease solved by protein folding game players.,Khatib F, Dimaio F, Cooper S, Kazmierczyk M, Gilski M, Krzywda S, Zabranska H, Pichova I, Thompson J, Popovic Z, Jaskolski M, Baker D Nat Struct Mol Biol. 2011 Sep 18. doi: 10.1038/nsmb.2119. PMID:21926992<ref>PMID:21926992</ref>
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The line below this paragraph, containing "STRUCTURE_3sqf", creates the "Structure Box" on the page.
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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or leave the SCENE parameter empty for the default display.
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-->
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{{STRUCTURE_3sqf| PDB=3sqf | SCENE= }}
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===Crystal structure of monomeric M-PMV retroviral protease===
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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</div>
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== References ==
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<!--
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_21926992}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 21926992 is the PubMed ID number.
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</StructureSection>
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[[Category: Mpmv]]
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{{ABSTRACT_PUBMED_21926992}}
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==About this Structure==
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[[3sqf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mason-pfizer_monkey_virus Mason-pfizer monkey virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SQF OCA].
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==Reference==
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<ref group="xtra">PMID:021926992</ref><ref group="xtra">PMID:009636364</ref><ref group="xtra">PMID:014568536</ref><ref group="xtra">PMID:002536902</ref><ref group="xtra">PMID:002548279</ref><references group="xtra"/>
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[[Category: Mason-pfizer monkey virus]]
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[[Category: Baker, D.]]
[[Category: Baker, D.]]
[[Category: Cooper, S.]]
[[Category: Cooper, S.]]

Revision as of 05:26, 5 June 2014

Crystal structure of monomeric M-PMV retroviral protease

3sqf, resolution 1.63Å

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