3sx0
From Proteopedia
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| - | ''' | + | ==Crystal structure of Dot1l in complex with a brominated SAH analog== |
| + | <StructureSection load='3sx0' size='340' side='right' caption='[[3sx0]], [[Resolution|resolution]] 2.28Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3sx0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SX0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SX0 FirstGlance]. <br> | ||
| + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SX0:(2S)-2-AMINO-4-({[(2S,3S,4R,5R)-5-(4-AMINO-5-BROMO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL}SULFANYL)BUTANOIC+ACID+(NON-PREFERRED+NAME)'>SX0</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene><br> | ||
| + | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DOT1L, KIAA1814, KMT4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
| + | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] </span></td></tr> | ||
| + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sx0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sx0 RCSB], [http://www.ebi.ac.uk/pdbsum/3sx0 PDBsum]</span></td></tr> | ||
| + | <table> | ||
| - | + | ==See Also== | |
| - | + | *[[Histone methyltransferase|Histone methyltransferase]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Histone-lysine N-methyltransferase]] | |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Arrowsmith, C H.]] | ||
| + | [[Category: Bountra, C.]] | ||
| + | [[Category: Brown, P J.]] | ||
| + | [[Category: Edwards, A M.]] | ||
| + | [[Category: Li, Y.]] | ||
| + | [[Category: Nguyen, K T.]] | ||
| + | [[Category: SGC, Structural Genomics Consortium.]] | ||
| + | [[Category: Schapira, M.]] | ||
| + | [[Category: Smil, D.]] | ||
| + | [[Category: Tempel, W.]] | ||
| + | [[Category: Vedadi, M.]] | ||
| + | [[Category: Weigelt, J.]] | ||
| + | [[Category: Wernimont, A K.]] | ||
| + | [[Category: Yu, W.]] | ||
| + | [[Category: Epigenetic]] | ||
| + | [[Category: Histone]] | ||
| + | [[Category: Methyltransferase]] | ||
| + | [[Category: Sgc]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Structural genomics consortium]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 05:30, 5 June 2014
Crystal structure of Dot1l in complex with a brominated SAH analog
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Categories: Histone-lysine N-methyltransferase | Homo sapiens | Arrowsmith, C H. | Bountra, C. | Brown, P J. | Edwards, A M. | Li, Y. | Nguyen, K T. | SGC, Structural Genomics Consortium. | Schapira, M. | Smil, D. | Tempel, W. | Vedadi, M. | Weigelt, J. | Wernimont, A K. | Yu, W. | Epigenetic | Histone | Methyltransferase | Sgc | Structural genomic | Structural genomics consortium | Transferase
